Clinical challenges in interpreting multiple pathogenic mutations in single patients

Clinical challenges in interpreting multiple pathogenic mutations in single patients

Abstract Background In the past two decades, genetic testing for cancer risk assessment has entered mainstream clinical practice due to the availability of low-cost panels of multiple cancer-associated genes. However, the clinical value of multiple-gene panels for cancer susceptibility is not well e...

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Bibliographic Details
Main Authors: Christa Slaught, Elizabeth G. Berry, Lindsay Bacik, Alison H. Skalet, George Anadiotis, Therese Tuohy, Sancy A. Leachman
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Melanoma
Genetics
Compound heterozygosity
BAP-1
MSH6
RECQL4
Online Access:https://doi.org/10.1186/s13053-021-00172-3

Internet

https://doi.org/10.1186/s13053-021-00172-3

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