Development of a cultivation process for the enhancement of human interferon alpha 2b production in the oleaginous yeast, <it>Yarrowia lipolytica</it>

Development of a cultivation process for the enhancement of human interferon alpha 2b production in the oleaginous yeast, <it>Yarrowia lipolytica</it>

<p>Abstract</p> <p>Background</p> <p>As an oleaginous yeast, <it>Yarrowia lipolytica </it>is able to assimilate hydrophobic substrates. This led to the isolation of several promoters of key enzymes of this catabolic pathway. Less is known about the behavior...

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Bibliographic Details
Main Authors: Gasmi Najla, Ayed Atef, Ammar Billel, Zrigui Rim, Nicaud Jean-Marc, Kallel Héla
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Microbial Cell Factories
Subjects:
<it>Yarrowia lipolytica</it>
POX2 promoter
induction strategy
high cell density culture
recombinant human interferon α2b
Online Access:http://www.microbialcellfactories.com/content/10/1/90

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