Breast cancer mammospheres secrete Adrenomedullin to induce lipolysis and browning of adjacent adipocytes

Breast cancer mammospheres secrete Adrenomedullin to induce lipolysis and browning of adjacent adipocytes

Abstract Background Cancer cells cooperate with cells that compose their environment to promote tumor growth and invasion. Among them, adipocytes provide lipids used as a source of energy by cancer cells and adipokines that contribute to tumor expansion. Mechanisms supporting the dynamic interaction...

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Bibliographic Details
Main Authors: Martin Paré, Cédric Y. Darini, Xi Yao, Bérengère Chignon-Sicard, Samah Rekima, Simon Lachambre, Virginie Virolle, Adriana Aguilar-Mahecha, Mark Basik, Christian Dani, Annie Ladoux
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Cancer
Subjects:
Adipocytes
Breast cancer
Adrenomedullin
Lipolysis
Browning
UCP1
Online Access:http://link.springer.com/article/10.1186/s12885-020-07273-7

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