Development of an algorithm for evaluating the impact of measurement variability on response categorization in oncology trials

Abstract Background Radiologic assessments of baseline and post-treatment tumor burden are subject to measurement variability, but the impact of this variability on the objective response rate (ORR) and progression rate in specific trials has been unpredictable on a practical level. In this study, w...

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Bibliographic Details
Main Authors: Jeong-Hwa Yoon, Soon Ho Yoon, Seokyung Hahn
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12874-019-0727-7