Reduction of pluripotent gene expression in murine embryonic stem cells exposed to mechanical loading or Cyclo RGD peptide
Abstract Background Self-renewal and differentiation of embryonic stem cells (ESCs) is directed by biological and/or physical cues that regulate multiple signaling cascades. We have previously shown that mESCs seeded in a type I collagen matrix demonstrate a loss of pluripotent marker expression and...
Main Authors: | Olesja Hazenbiller, Neil A. Duncan, Roman J. Krawetz |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-11-01
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Series: | BMC Cell Biology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12860-017-0148-6 |
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