| Summary: | Background: Metastasis to post-surgical pituitary adenoma (PA) is extremely rare.
Case description: A 53-year-old man previously underwent endoscopic transsphenoidal surgery (TSS) for resection of PA and had stable annual post-operative magnetic resonance imaging for several years. Later, he had abdominal surgery for newly discovered malignant colon neoplasm. In addition, evidence of multiple lung metastases was subsequently discovered prompting chemotherapy. The patient, before his second TSS, presented with symptomatic visual field defect from rapidly enlarging residual PA causing mass effect to optic apparatus. Subsequently, second operation was performed with unremarkable intraoperative findings and postoperative course. However, histopathology revealed metastatic adenocarcinoma inside the PA.
Conclusions: This is the first reported case of metastasis from colon cancer to post-TSS PA.
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