circRPS16 Promotes Proliferation and Invasion of Hepatocellular Carcinoma by Sponging miR-876-5p to Upregulate SPINK1

circRPS16 Promotes Proliferation and Invasion of Hepatocellular Carcinoma by Sponging miR-876-5p to Upregulate SPINK1

The roles of serine protease inhibitor Kazal type 1 (SPINK1) in multiple types of cancers have been significantly documented. However, its specific roles in hepatocellular carcinoma (HCC) remain to be investigated. This study found that SPINK1 is upregulated in HCC and its upregulation correlates wi...

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Bibliographic Details
Main Authors: Shuwen Lin, Ye Lin, Zhongshi Wu, Wuzheng Xia, Chenglong Miao, Tianyi Peng, Zhen Zhao, Chenggang Ji, Zhikang Mo, Xi Liu, Zhixiang Jian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
hepatocellular carcinoma (HCC)
circRPS16
miR-876-5p
SPINK1
proliferation
invasion
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.724415/full

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