Dendritic cell-directed vaccination with a lentivector encoding PSCA for prostate cancer in mice.

Many studies have demonstrated that prostate stem cell antigen (PSCA) is an attractive target for immunotherapy based on its overexpression in prostate tumor tissue, especially in some metastatic tissues. In this study, we evaluated dendritic cell (DC)-directed lentiviral vector (DCLV) encoding muri...

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Bibliographic Details
Main Authors: Liang Xiao, Kye-Il Joo, Matthew Lim, Pin Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3490948?pdf=render