The Role of Community Pharmacists in the Detection of Clinically Relevant Drug-Related Problems in Chronic Kidney Disease Patients
Community pharmacists (CPs) have traditionally had limited access to patients’ estimated glomerular filtration rate (eGFR) during the medication-dispensing process. The increasing access to shared electronic health records is making eGFR available, but the skills needed to detect and manage clinical...
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doaj-d90b00959c534d888697ecbba63154552020-11-25T03:33:37ZengMDPI AGPharmacy2226-47872020-05-018898910.3390/pharmacy8020089The Role of Community Pharmacists in the Detection of Clinically Relevant Drug-Related Problems in Chronic Kidney Disease PatientsCéline Mongaret0Léa Aubert1Amélie Lestrille2Victorine Albaut3Pierre Kreit4Emmanuelle Herlem5Natacha Noel6Fatouma Touré7François Lallier8Florian Slimano9the MIRPhO Investigators StudyFaculty of Pharmacy, Reims University, 51 rue Cognacq-Jay, 51100 Reims, FranceFaculty of Pharmacy, Reims University, 51 rue Cognacq-Jay, 51100 Reims, FranceFaculty of Pharmacy, Reims University, 51 rue Cognacq-Jay, 51100 Reims, FranceFaculty of Pharmacy, Reims University, 51 rue Cognacq-Jay, 51100 Reims, FranceUnion Régionale des Professionnels de Santé (URPS) Pharmacien Grand Est, 18 quai Claude Le Lorrain, 54000 Nancy, FranceDepartment of Pharmacy, CHU Reims, Avenue du Général Koenig, 51100 Reims, FranceDepartment of Nephrology, CHU Reims, Avenue du Général Koenig, 51100 Reims, FranceDepartment of Nephrology, CHU Reims, Avenue du Général Koenig, 51100 Reims, FranceFaculty of Medicine, Reims University, 51 rue Cognacq-Jay, 51100 Reims, FranceFaculty of Pharmacy, Reims University, 51 rue Cognacq-Jay, 51100 Reims, FranceCommunity pharmacists (CPs) have traditionally had limited access to patients’ estimated glomerular filtration rate (eGFR) during the medication-dispensing process. The increasing access to shared electronic health records is making eGFR available, but the skills needed to detect and manage clinically relevant drug-related problems (DRPs) are poorly documented. The primary objective of this study was to investigate the role of CPs in the medication-dispensation process for elderly patients with renal impairment. A total of 70 CPs participated in this 6 month study. Community pharmacists asked all patients ≥65 years to bring their laboratory test values for the next medication-dispensing process. Drug-related problem detection rates were compared between CPs (prospective period) and expert pharmacists (retrospectively). The clinical relevance of each DRP was assessed by nephrologists and general practitioners using an appropriate tool. Community pharmacists recruited n = 442 patients with eGFR < 60 mL/min/1.73 m<sup>2</sup> and detected n = 99 DRPs, whereas expert pharmacists detected n = 184 DRPs. The most frequently detected DRPs were dosage problems and contraindications. According to assessment by clinicians, CPs and expert pharmacists identified 54.0% and 84.7% of clinically relevant DRPs, respectively. This study suggests a positive impact of the systematic availability of eGFR to CPs on the detection of several DRPs with clinical relevance.https://www.mdpi.com/2226-4787/8/2/89chronic kidney diseasedrug-related problemscommunity pharmacistestimated glomerular filtration rate |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Céline Mongaret Léa Aubert Amélie Lestrille Victorine Albaut Pierre Kreit Emmanuelle Herlem Natacha Noel Fatouma Touré François Lallier Florian Slimano the MIRPhO Investigators Study |
spellingShingle |
Céline Mongaret Léa Aubert Amélie Lestrille Victorine Albaut Pierre Kreit Emmanuelle Herlem Natacha Noel Fatouma Touré François Lallier Florian Slimano the MIRPhO Investigators Study The Role of Community Pharmacists in the Detection of Clinically Relevant Drug-Related Problems in Chronic Kidney Disease Patients Pharmacy chronic kidney disease drug-related problems community pharmacist estimated glomerular filtration rate |
author_facet |
Céline Mongaret Léa Aubert Amélie Lestrille Victorine Albaut Pierre Kreit Emmanuelle Herlem Natacha Noel Fatouma Touré François Lallier Florian Slimano the MIRPhO Investigators Study |
author_sort |
Céline Mongaret |
title |
The Role of Community Pharmacists in the Detection of Clinically Relevant Drug-Related Problems in Chronic Kidney Disease Patients |
title_short |
The Role of Community Pharmacists in the Detection of Clinically Relevant Drug-Related Problems in Chronic Kidney Disease Patients |
title_full |
The Role of Community Pharmacists in the Detection of Clinically Relevant Drug-Related Problems in Chronic Kidney Disease Patients |
title_fullStr |
The Role of Community Pharmacists in the Detection of Clinically Relevant Drug-Related Problems in Chronic Kidney Disease Patients |
title_full_unstemmed |
The Role of Community Pharmacists in the Detection of Clinically Relevant Drug-Related Problems in Chronic Kidney Disease Patients |
title_sort |
role of community pharmacists in the detection of clinically relevant drug-related problems in chronic kidney disease patients |
publisher |
MDPI AG |
series |
Pharmacy |
issn |
2226-4787 |
publishDate |
2020-05-01 |
description |
Community pharmacists (CPs) have traditionally had limited access to patients’ estimated glomerular filtration rate (eGFR) during the medication-dispensing process. The increasing access to shared electronic health records is making eGFR available, but the skills needed to detect and manage clinically relevant drug-related problems (DRPs) are poorly documented. The primary objective of this study was to investigate the role of CPs in the medication-dispensation process for elderly patients with renal impairment. A total of 70 CPs participated in this 6 month study. Community pharmacists asked all patients ≥65 years to bring their laboratory test values for the next medication-dispensing process. Drug-related problem detection rates were compared between CPs (prospective period) and expert pharmacists (retrospectively). The clinical relevance of each DRP was assessed by nephrologists and general practitioners using an appropriate tool. Community pharmacists recruited n = 442 patients with eGFR < 60 mL/min/1.73 m<sup>2</sup> and detected n = 99 DRPs, whereas expert pharmacists detected n = 184 DRPs. The most frequently detected DRPs were dosage problems and contraindications. According to assessment by clinicians, CPs and expert pharmacists identified 54.0% and 84.7% of clinically relevant DRPs, respectively. This study suggests a positive impact of the systematic availability of eGFR to CPs on the detection of several DRPs with clinical relevance. |
topic |
chronic kidney disease drug-related problems community pharmacist estimated glomerular filtration rate |
url |
https://www.mdpi.com/2226-4787/8/2/89 |
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