Exposure to triclosan among the Canadian population: Results of the Canadian Health Measures Survey (2009–2013)
Triclosan is a broad-spectrum antimicrobial additive in consumer products that has been detected in human populations globally. The purpose of this study was to assess triclosan exposure among the Canadian population using urinary triclosan as a biomarker. Data from the Canadian Health Measures Surv...
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doaj-d91036c3e9a94bac9e6711b15af557822020-11-24T21:56:15ZengElsevierEnvironment International0160-41202019-02-011232938Exposure to triclosan among the Canadian population: Results of the Canadian Health Measures Survey (2009–2013)Amanda Juric0Kavita Singh1Xue Feng Hu2Hing Man Chan3Department of Biology, University of Ottawa, Ontario K1N 6N5, CanadaDepartment of Biology, University of Ottawa, Ontario K1N 6N5, CanadaDepartment of Biology, University of Ottawa, Ontario K1N 6N5, CanadaCorresponding author.; Department of Biology, University of Ottawa, Ontario K1N 6N5, CanadaTriclosan is a broad-spectrum antimicrobial additive in consumer products that has been detected in human populations globally. The purpose of this study was to assess triclosan exposure among the Canadian population using urinary triclosan as a biomarker. Data from the Canadian Health Measures Survey (CHMS) that reported triclosan concentrations in 8195 urine samples collected from Cycle 2 (2009–2011) and Cycle 3 (2012−2013) were analyzed. Triclosan was detected in 69.8% of samples with the geometric mean concentrations of 16 μg/L (16 μg/g creatinine) for the total population, 13 μg/L (13 μg/g creatinine) for children (3–19 years of age), and 16 μg/L (17 μg/g creatinine) for adults. Triclosan concentrations significantly differed by age, income, education, and employment in healthcare occupations, but not by race/ethnicity, sex, region of residence, or drinking water preferences or sources. Linear regression models were used to identify factors associated with urinary triclosan concentration. Results showed that household income was associated with higher urinary triclosan concentrations in both children and adults. Employed in healthcare occupations were associated with higher urinary triclosan concentrations in adults. Triclosan exposure at the 99th percentile was below the Biomonitoring Equivalents based on reference dose, suggesting that health risks to the Canadian population from triclosan exposure were low. Keywords: Triclosan, Urine concentrations, Adults, Children, Canada, Canadian health measure surveyhttp://www.sciencedirect.com/science/article/pii/S0160412018317781 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Amanda Juric Kavita Singh Xue Feng Hu Hing Man Chan |
spellingShingle |
Amanda Juric Kavita Singh Xue Feng Hu Hing Man Chan Exposure to triclosan among the Canadian population: Results of the Canadian Health Measures Survey (2009–2013) Environment International |
author_facet |
Amanda Juric Kavita Singh Xue Feng Hu Hing Man Chan |
author_sort |
Amanda Juric |
title |
Exposure to triclosan among the Canadian population: Results of the Canadian Health Measures Survey (2009–2013) |
title_short |
Exposure to triclosan among the Canadian population: Results of the Canadian Health Measures Survey (2009–2013) |
title_full |
Exposure to triclosan among the Canadian population: Results of the Canadian Health Measures Survey (2009–2013) |
title_fullStr |
Exposure to triclosan among the Canadian population: Results of the Canadian Health Measures Survey (2009–2013) |
title_full_unstemmed |
Exposure to triclosan among the Canadian population: Results of the Canadian Health Measures Survey (2009–2013) |
title_sort |
exposure to triclosan among the canadian population: results of the canadian health measures survey (2009–2013) |
publisher |
Elsevier |
series |
Environment International |
issn |
0160-4120 |
publishDate |
2019-02-01 |
description |
Triclosan is a broad-spectrum antimicrobial additive in consumer products that has been detected in human populations globally. The purpose of this study was to assess triclosan exposure among the Canadian population using urinary triclosan as a biomarker. Data from the Canadian Health Measures Survey (CHMS) that reported triclosan concentrations in 8195 urine samples collected from Cycle 2 (2009–2011) and Cycle 3 (2012−2013) were analyzed. Triclosan was detected in 69.8% of samples with the geometric mean concentrations of 16 μg/L (16 μg/g creatinine) for the total population, 13 μg/L (13 μg/g creatinine) for children (3–19 years of age), and 16 μg/L (17 μg/g creatinine) for adults. Triclosan concentrations significantly differed by age, income, education, and employment in healthcare occupations, but not by race/ethnicity, sex, region of residence, or drinking water preferences or sources. Linear regression models were used to identify factors associated with urinary triclosan concentration. Results showed that household income was associated with higher urinary triclosan concentrations in both children and adults. Employed in healthcare occupations were associated with higher urinary triclosan concentrations in adults. Triclosan exposure at the 99th percentile was below the Biomonitoring Equivalents based on reference dose, suggesting that health risks to the Canadian population from triclosan exposure were low. Keywords: Triclosan, Urine concentrations, Adults, Children, Canada, Canadian health measure survey |
url |
http://www.sciencedirect.com/science/article/pii/S0160412018317781 |
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