Recurrent/moderate hypoglycemia induces hippocampal dendritic injury, microglial activation, and cognitive impairment in diabetic rats

Recurrent/moderate hypoglycemia induces hippocampal dendritic injury, microglial activation, and cognitive impairment in diabetic rats

<p>Abstract</p> <p>Background</p> <p>Recurrent/moderate (R/M) hypoglycemia is common in type 1 diabetes. Although mild or moderate hypoglycemia is not life-threatening, if recurrent, it may cause cognitive impairment. In the present study, we sought to determine whether...

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Bibliographic Details
Main Authors: Won Seok, Yoo Byung, Kauppinen Tiina M, Choi Bo, Kim Jin, Jang Bong, Lee Min, Sohn Min, Liu Jialing, Swanson Raymond A, Suh Sang
Format: Article
Language:English
Published: BMC 2012-07-01
Series:Journal of Neuroinflammation
Subjects:
Recurrent/moderate hypoglycemia
Dendrite
Superoxide
Lipid peroxidation
Neuron death
Microglial activation
NADPH oxidase
Apocynin
Online Access:http://www.jneuroinflammation.com/content/9/1/182

Internet

http://www.jneuroinflammation.com/content/9/1/182

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