| Summary: | AIM: To evaluate the change of retinal nerve fiber layer thickness(RNFLT)after laser <i>in situ</i> keratomileusis(LASIK)by three dimensional frequency domain optical coherent tomography(3D-OCT). <p>METHODS:Eighty-three patients(83 right eyes)who underwent LASIK operation were recruited. RNFLT was performed by 3D-OCT preoperatively and 1 day, 1 week, 1 month and 3 months postoperatively. The data was analyzed with repeated measures ANOVA and paired <i>t</i> test. <p>RESULTS: After the comparisons of the RNFL thickness among different time points, we found no statistical differences excluding the RNFLT of superior, nasal and 12, 1-4 o'clock sectors through the repeated measures with ANOVA.Then using paired <i>t</i> test for further analysis, the difference was not remained in the follow-up observation. There was also a significant correlation between RNFLT and diopter(superior <i>r</i>=-0.316, <i>P=</i>0.004; nasal <i>r</i>=-0.456, <i>P<</i>0.001)and laser cutting time(superior <i>r</i>=0.341, <i>P=</i>0.002; nasal <i>r</i>=0.471, <i>P<</i>0.001), but no significant correlation between RNFLT and age and suction time.<p>CONCLUSION: There is no change of RNFLT after LASIK during the follow-up.
|
|---|
