Comprehensive Analysis of Key Genes, Signaling Pathways and miRNAs in Human Knee Osteoarthritis: Based on Bioinformatics

Comprehensive Analysis of Key Genes, Signaling Pathways and miRNAs in Human Knee Osteoarthritis: Based on Bioinformatics

Background: Osteoarthritis (OA) is one of the main causes of disability in the elderly population, accompanied by a series of underlying pathologic changes, such as cartilage degradation, synovitis, subchondral bone sclerosis, and meniscus injury. The present study aimed to identify key genes, signa...

Full description

Bibliographic Details
Main Authors: Liang Chang, Hao Yao, Zhi Yao, Kevin Ki-Wai Ho, Michael Tim-Yun Ong, Bingyang Dai, Wenxue Tong, Jiankun Xu, Ling Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Pharmacology
Subjects:
osteoarthiritis
overlapping genes
signaling pathways
miRNAs
bioinformatics
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.730587/full

Similar Items

Similar Items