Rapid Mass Spectrometric Study of a Supercritical CO<sub>2</sub>-extract from Woody Liana <i>Schisandra chinensis</i> by HPLC-SPD-ESI-MS/MS

Rapid Mass Spectrometric Study of a Supercritical CO<sub>2</sub>-extract from Woody Liana <i>Schisandra chinensis</i> by HPLC-SPD-ESI-MS/MS

Woody liana <i>Schisandra chinensis</i> contains valuable lignans, which are phenylpropanoids with valuable biological activity. Among green and selective extraction methods, supercritical carbon dioxide (SC-CO<sub>2</sub>) was shown to be the method of choice for the recover...

Full description

Bibliographic Details
Main Authors: Mayya Razgonova, Alexander Zakharenko, Konstantin Pikula, Ekaterina Kim, Valery Chernyshev, Sezai Ercisli, Giancarlo Cravotto, Kirill Golokhvast
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Molecules
Subjects:
<i>Schisandra chinensis</i>
supercritical fluid extraction
HPLC-SPD-ESI-MS/MS
lignans
Online Access:https://www.mdpi.com/1420-3049/25/11/2689
id doaj-d932cf14fbb34b94b829526acc4a43f6
record_format Article
spelling doaj-d932cf14fbb34b94b829526acc4a43f62020-11-25T03:07:59ZengMDPI AGMolecules1420-30492020-06-01252689268910.3390/molecules25112689Rapid Mass Spectrometric Study of a Supercritical CO<sub>2</sub>-extract from Woody Liana <i>Schisandra chinensis</i> by HPLC-SPD-ESI-MS/MSMayya Razgonova0Alexander Zakharenko1Konstantin Pikula2Ekaterina Kim3Valery Chernyshev4Sezai Ercisli5Giancarlo Cravotto6Kirill Golokhvast7REC Nanotechnology, School of Engineering, Far Eastern Federal University, Sukhanova 8, 690950 Vladivostok, RussiaREC Nanotechnology, School of Engineering, Far Eastern Federal University, Sukhanova 8, 690950 Vladivostok, RussiaREC Nanotechnology, School of Engineering, Far Eastern Federal University, Sukhanova 8, 690950 Vladivostok, RussiaREC Nanotechnology, School of Engineering, Far Eastern Federal University, Sukhanova 8, 690950 Vladivostok, RussiaREC Nanotechnology, School of Engineering, Far Eastern Federal University, Sukhanova 8, 690950 Vladivostok, RussiaAgricultural Faculty, Department of Horticulture, Ataturk University, Erzurum 25240, TurkeyDipartimento di Scienza e Technologia del Farmaco, University of Turin, Via P. Giuria 9, 10125 Turin, ItalyREC Nanotechnology, School of Engineering, Far Eastern Federal University, Sukhanova 8, 690950 Vladivostok, RussiaWoody liana <i>Schisandra chinensis</i> contains valuable lignans, which are phenylpropanoids with valuable biological activity. Among green and selective extraction methods, supercritical carbon dioxide (SC-CO<sub>2</sub>) was shown to be the method of choice for the recovery of these naturally occurring compounds. Carbon dioxide (CO<sub>2</sub>) was the solvent with the flow rate (10−25 g/min) with 2% ethanol as co-solvent. In this piece of work operative parameters and working conditions were optimized by experimenting with different pressures (200–400 bars) and temperatures (40–60 °C). The extraction time varied from 60 to 120 min. HPLC-SPD-ESI -MS/MS techniques were applied to detect target analytes. Twenty-six different lignans were identified in the S. <i>chinensis</i> SC-CO<sub>2</sub> extracts.https://www.mdpi.com/1420-3049/25/11/2689<i>Schisandra chinensis</i>supercritical fluid extractionHPLC-SPD-ESI-MS/MSlignans
collection DOAJ
language English
format Article
sources DOAJ
author Mayya Razgonova
Alexander Zakharenko
Konstantin Pikula
Ekaterina Kim
Valery Chernyshev
Sezai Ercisli
Giancarlo Cravotto
Kirill Golokhvast
spellingShingle Mayya Razgonova
Alexander Zakharenko
Konstantin Pikula
Ekaterina Kim
Valery Chernyshev
Sezai Ercisli
Giancarlo Cravotto
Kirill Golokhvast
Rapid Mass Spectrometric Study of a Supercritical CO<sub>2</sub>-extract from Woody Liana <i>Schisandra chinensis</i> by HPLC-SPD-ESI-MS/MS
Molecules
<i>Schisandra chinensis</i>
supercritical fluid extraction
HPLC-SPD-ESI-MS/MS
lignans
author_facet Mayya Razgonova
Alexander Zakharenko
Konstantin Pikula
Ekaterina Kim
Valery Chernyshev
Sezai Ercisli
Giancarlo Cravotto
Kirill Golokhvast
author_sort Mayya Razgonova
title Rapid Mass Spectrometric Study of a Supercritical CO<sub>2</sub>-extract from Woody Liana <i>Schisandra chinensis</i> by HPLC-SPD-ESI-MS/MS
title_short Rapid Mass Spectrometric Study of a Supercritical CO<sub>2</sub>-extract from Woody Liana <i>Schisandra chinensis</i> by HPLC-SPD-ESI-MS/MS
title_full Rapid Mass Spectrometric Study of a Supercritical CO<sub>2</sub>-extract from Woody Liana <i>Schisandra chinensis</i> by HPLC-SPD-ESI-MS/MS
title_fullStr Rapid Mass Spectrometric Study of a Supercritical CO<sub>2</sub>-extract from Woody Liana <i>Schisandra chinensis</i> by HPLC-SPD-ESI-MS/MS
title_full_unstemmed Rapid Mass Spectrometric Study of a Supercritical CO<sub>2</sub>-extract from Woody Liana <i>Schisandra chinensis</i> by HPLC-SPD-ESI-MS/MS
title_sort rapid mass spectrometric study of a supercritical co<sub>2</sub>-extract from woody liana <i>schisandra chinensis</i> by hplc-spd-esi-ms/ms
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2020-06-01
description Woody liana <i>Schisandra chinensis</i> contains valuable lignans, which are phenylpropanoids with valuable biological activity. Among green and selective extraction methods, supercritical carbon dioxide (SC-CO<sub>2</sub>) was shown to be the method of choice for the recovery of these naturally occurring compounds. Carbon dioxide (CO<sub>2</sub>) was the solvent with the flow rate (10−25 g/min) with 2% ethanol as co-solvent. In this piece of work operative parameters and working conditions were optimized by experimenting with different pressures (200–400 bars) and temperatures (40–60 °C). The extraction time varied from 60 to 120 min. HPLC-SPD-ESI -MS/MS techniques were applied to detect target analytes. Twenty-six different lignans were identified in the S. <i>chinensis</i> SC-CO<sub>2</sub> extracts.
topic <i>Schisandra chinensis</i>
supercritical fluid extraction
HPLC-SPD-ESI-MS/MS
lignans
url https://www.mdpi.com/1420-3049/25/11/2689
work_keys_str_mv AT mayyarazgonova rapidmassspectrometricstudyofasupercriticalcosub2subextractfromwoodylianaischisandrachinensisibyhplcspdesimsms
AT alexanderzakharenko rapidmassspectrometricstudyofasupercriticalcosub2subextractfromwoodylianaischisandrachinensisibyhplcspdesimsms
AT konstantinpikula rapidmassspectrometricstudyofasupercriticalcosub2subextractfromwoodylianaischisandrachinensisibyhplcspdesimsms
AT ekaterinakim rapidmassspectrometricstudyofasupercriticalcosub2subextractfromwoodylianaischisandrachinensisibyhplcspdesimsms
AT valerychernyshev rapidmassspectrometricstudyofasupercriticalcosub2subextractfromwoodylianaischisandrachinensisibyhplcspdesimsms
AT sezaiercisli rapidmassspectrometricstudyofasupercriticalcosub2subextractfromwoodylianaischisandrachinensisibyhplcspdesimsms
AT giancarlocravotto rapidmassspectrometricstudyofasupercriticalcosub2subextractfromwoodylianaischisandrachinensisibyhplcspdesimsms
AT kirillgolokhvast rapidmassspectrometricstudyofasupercriticalcosub2subextractfromwoodylianaischisandrachinensisibyhplcspdesimsms
_version_ 1724667825866407936

Similar Items