Chronic Stress Produces Persistent Increases in Plasma Corticosterone, Reductions in Brain and Cardiac Nitric Oxide Production, and Delayed Alterations in Endothelial Function in Young Prehypertensive Rats

Chronic Stress Produces Persistent Increases in Plasma Corticosterone, Reductions in Brain and Cardiac Nitric Oxide Production, and Delayed Alterations in Endothelial Function in Young Prehypertensive Rats

This study was designed to investigate whether oxidative stress, nitric oxide (NO) deficiency and/or endothelial dysfunction (ED) are present in young borderline hypertensive rats (BHR) and whether these pathologies can be causally involved in the initiation of blood pressure (BP) increases. Additio...

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Bibliographic Details
Main Authors: Iveta Bernatova, Angelika Puzserova, Peter Balis, Natalia Sestakova, Martina Horvathova, Zuzana Kralovicova, Ingrid Zitnanova
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Physiology
Subjects:
crowding stress
borderline hypertension
oxidative stress
corticosterone
nitric oxide
endothelial dysfunction
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01179/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.01179/full

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