Recovery of Antimicrobials and Bioaccessible Isoflavones and Phenolics from Soybean (Glycine max) Meal by Aqueous Extraction

Soybeans display strategic potential in food security as a source of protein and functional bioactives for human consumption. Polyphenols and other bioactive compounds can be recovered after an aqueous extraction from soybean meal, a byproduct of soy oil refining. The objective of the present study...

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Main Authors: Cyntia S. Freitas, Genilton Alves da Silva, Daniel Perrone, Mauricio A. Vericimo, Diego dos S. Baião, Patrícia R. Pereira, Vânia M. F. Paschoalin, Eduardo M. Del Aguila
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/24/1/74
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spelling doaj-d9512d30fa6043b68a217654ea42ca182020-11-24T23:26:33ZengMDPI AGMolecules1420-30492018-12-012417410.3390/molecules24010074molecules24010074Recovery of Antimicrobials and Bioaccessible Isoflavones and Phenolics from Soybean (Glycine max) Meal by Aqueous ExtractionCyntia S. Freitas0Genilton Alves da Silva1Daniel Perrone2Mauricio A. Vericimo3Diego dos S. Baião4Patrícia R. Pereira5Vânia M. F. Paschoalin6Eduardo M. Del Aguila7Instituto de Química, Universidade Federal do Rio de Janeiro, Avenida Athos da Silveira Ramos 149, 21941-909 Rio de Janeiro, BrazilInstituto de Química, Universidade Federal do Rio de Janeiro, Avenida Athos da Silveira Ramos 149, 21941-909 Rio de Janeiro, BrazilInstituto de Química, Universidade Federal do Rio de Janeiro, Avenida Athos da Silveira Ramos 149, 21941-909 Rio de Janeiro, BrazilInstituto de Biologia, Universidade Federal Fluminense, Niterói, 4020-141 Rio de Janeiro, BrazilInstituto de Química, Universidade Federal do Rio de Janeiro, Avenida Athos da Silveira Ramos 149, 21941-909 Rio de Janeiro, BrazilInstituto de Química, Universidade Federal do Rio de Janeiro, Avenida Athos da Silveira Ramos 149, 21941-909 Rio de Janeiro, BrazilInstituto de Química, Universidade Federal do Rio de Janeiro, Avenida Athos da Silveira Ramos 149, 21941-909 Rio de Janeiro, BrazilInstituto de Química, Universidade Federal do Rio de Janeiro, Avenida Athos da Silveira Ramos 149, 21941-909 Rio de Janeiro, BrazilSoybeans display strategic potential in food security as a source of protein and functional bioactives for human consumption. Polyphenols and other bioactive compounds can be recovered after an aqueous extraction from soybean meal, a byproduct of soy oil refining. The objective of the present study was to compile and quantify compounds from soybean oil refinery by-products, providing information about valuable bioactive phytochemicals, their bioaccessibility and potential bioactivities. Genistin, daidzin, glycitin and malonylgenistin were the predominant isoflavones, and the overall bioaccessibility of their glycosidic forms was of nearly 75%. Sixteen phenolics were identified and caffeic acid, 5-caffeoylquinic chlorogenic acid and hesperidin were the most predominant. Approximately 30% of gallic acid, syringic acid, vanillic acid and myricetin were released and the antioxidant capacity of aqueous extract was enhanced after simulated in vitro gastro intestinal digestion. The ability of aqueous soybean meal extract to inhibit lipid peroxidation was higher than natural and synthetic food antioxidants. Antimicrobial activity against several foodborne pathogens and antitumoral activity towards human glioblastoma cell line were also observed, but the aqueous extract showed no cytotoxicity to healthy murine cells. Compounds derived from the aqueous soybean meal extract have the potential to be used as health promoting agents.http://www.mdpi.com/1420-3049/24/1/74extruded-soy materialpolyphenolsisoflavonesbioaccessibilitynon-cytotoxicantimicrobial and antimitogenic activities
collection DOAJ
language English
format Article
sources DOAJ
author Cyntia S. Freitas
Genilton Alves da Silva
Daniel Perrone
Mauricio A. Vericimo
Diego dos S. Baião
Patrícia R. Pereira
Vânia M. F. Paschoalin
Eduardo M. Del Aguila
spellingShingle Cyntia S. Freitas
Genilton Alves da Silva
Daniel Perrone
Mauricio A. Vericimo
Diego dos S. Baião
Patrícia R. Pereira
Vânia M. F. Paschoalin
Eduardo M. Del Aguila
Recovery of Antimicrobials and Bioaccessible Isoflavones and Phenolics from Soybean (Glycine max) Meal by Aqueous Extraction
Molecules
extruded-soy material
polyphenols
isoflavones
bioaccessibility
non-cytotoxic
antimicrobial and antimitogenic activities
author_facet Cyntia S. Freitas
Genilton Alves da Silva
Daniel Perrone
Mauricio A. Vericimo
Diego dos S. Baião
Patrícia R. Pereira
Vânia M. F. Paschoalin
Eduardo M. Del Aguila
author_sort Cyntia S. Freitas
title Recovery of Antimicrobials and Bioaccessible Isoflavones and Phenolics from Soybean (Glycine max) Meal by Aqueous Extraction
title_short Recovery of Antimicrobials and Bioaccessible Isoflavones and Phenolics from Soybean (Glycine max) Meal by Aqueous Extraction
title_full Recovery of Antimicrobials and Bioaccessible Isoflavones and Phenolics from Soybean (Glycine max) Meal by Aqueous Extraction
title_fullStr Recovery of Antimicrobials and Bioaccessible Isoflavones and Phenolics from Soybean (Glycine max) Meal by Aqueous Extraction
title_full_unstemmed Recovery of Antimicrobials and Bioaccessible Isoflavones and Phenolics from Soybean (Glycine max) Meal by Aqueous Extraction
title_sort recovery of antimicrobials and bioaccessible isoflavones and phenolics from soybean (glycine max) meal by aqueous extraction
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2018-12-01
description Soybeans display strategic potential in food security as a source of protein and functional bioactives for human consumption. Polyphenols and other bioactive compounds can be recovered after an aqueous extraction from soybean meal, a byproduct of soy oil refining. The objective of the present study was to compile and quantify compounds from soybean oil refinery by-products, providing information about valuable bioactive phytochemicals, their bioaccessibility and potential bioactivities. Genistin, daidzin, glycitin and malonylgenistin were the predominant isoflavones, and the overall bioaccessibility of their glycosidic forms was of nearly 75%. Sixteen phenolics were identified and caffeic acid, 5-caffeoylquinic chlorogenic acid and hesperidin were the most predominant. Approximately 30% of gallic acid, syringic acid, vanillic acid and myricetin were released and the antioxidant capacity of aqueous extract was enhanced after simulated in vitro gastro intestinal digestion. The ability of aqueous soybean meal extract to inhibit lipid peroxidation was higher than natural and synthetic food antioxidants. Antimicrobial activity against several foodborne pathogens and antitumoral activity towards human glioblastoma cell line were also observed, but the aqueous extract showed no cytotoxicity to healthy murine cells. Compounds derived from the aqueous soybean meal extract have the potential to be used as health promoting agents.
topic extruded-soy material
polyphenols
isoflavones
bioaccessibility
non-cytotoxic
antimicrobial and antimitogenic activities
url http://www.mdpi.com/1420-3049/24/1/74
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