Construction of a complete set of Neisseria meningitidis mutants and its use for the phenotypic profiling of this human pathogen
The bacterium Neisseria meningitidis causes life-threatening meningitis and sepsis. Here, Muir et al. construct a complete collection of defined mutants in protein-coding genes of this organism, which they use to identify its essential genome and to shed light on the functions of multiple genes.
Main Authors: | Alastair Muir, Ishwori Gurung, Ana Cehovin, Adelme Bazin, David Vallenet, Vladimir Pelicic |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-19347-y |
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