The influence of microRNAs and poly(A) tail length on endogenous mRNA–protein complexes
Abstract Background All mRNAs are bound in vivo by proteins to form mRNA–protein complexes (mRNPs), but changes in the composition of mRNPs during posttranscriptional regulation remain largely unexplored. Here, we have analyzed, on a transcriptome-wide scale, how microRNA-mediated repression modulat...
Main Authors: | Olivia S. Rissland, Alexander O. Subtelny, Miranda Wang, Andrew Lugowski, Beth Nicholson, John D. Laver, Sachdev S. Sidhu, Craig A. Smibert, Howard D. Lipshitz, David P. Bartel |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-10-01
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Series: | Genome Biology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13059-017-1330-z |
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