NS5A resistance – associated substitutions in chronic hepatitis C patients with direct acting antiviral treatment failure in Turkey

NS5A resistance – associated substitutions in chronic hepatitis C patients with direct acting antiviral treatment failure in Turkey

Objectives: Chronic hepatitis C (CHC) is now a more curable disease with new direct acting antivirals (DAA). Although high sustained virologic response rates, failures still occur in DAA regimens. Our objective in this study was to characterize the real-life presence of clinically relevant resistanc...

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Bibliographic Details
Main Authors: Murat Sayan, Figen Sarıgül Yıldırım, Sıla Akhan, Arzu Altunçekiç Yıldırım, Göktuğ Şirin, Mehmet Cabalak, Mehmet Demir, Selver Can, Gülden Ersöz, Engin Altıntaş, Fatih Ensaroğlu, Ayhan Akbulut, Alper Şener, Aydın Deveci
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:International Journal of Infectious Diseases
Subjects:
Hepatitis C
Hepatitis C virus
NS-5 protein
Treatment failure
Sequence analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971220301946

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