Microdroplet Protein Sensors on a Gold Surface with a Self-assembled Monolayer Treatment
<p>A new kind of microdroplet-based biological protein sensor is presented. The sensor was made by placing silicon oil on gold film with a self-assembled monolayer (SAM). The surface tension dominates the sensitivity of the sensor. Using mercaptoundecanoic acid (11-MUA) as the sensor’s SAM lay...
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Chinese Institute of Automation Engineers (CIAE) & Taiwan Smart Living Space Association (SMART LISA)
2012-03-01
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Online Access: | http://www.ausmt.org/index.php/AUSMT/article/view/116 |
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doaj-d97f77e0300d4defbe08e5c1d2edda402020-11-25T01:09:46ZengChinese Institute of Automation Engineers (CIAE) & Taiwan Smart Living Space Association (SMART LISA)International Journal of Automation and Smart Technology2223-97662012-03-0121434810.5875/ausmt.v2i1.11630Microdroplet Protein Sensors on a Gold Surface with a Self-assembled Monolayer TreatmentTzu-Chun Liao0J. Andrew Yeh1Department of Power Mechanical Engineering, National Tsing Hua UniversityInstitute of Nanoengineering and Microsystems, National Tsing-Hua University<p>A new kind of microdroplet-based biological protein sensor is presented. The sensor was made by placing silicon oil on gold film with a self-assembled monolayer (SAM). The surface tension dominates the sensitivity of the sensor. Using mercaptoundecanoic acid (11-MUA) as the sensor’s SAM layer, the sensor can detect 0.5 mg/ml, 20 μg/ml, and 0.4 μg/ml bovine serum albumin (BSA) protein solutions in a control volume of 0.5ml. The sensor’s reaction time for concentrations of 0.5 mg/ml, 20 μg/ml, and 0.4μg/ml protein solutions was 15, 60 and 120 minutes, respectively. As the size of microdroplet decreased, the change of contact angle increased.</p>http://www.ausmt.org/index.php/AUSMT/article/view/116microdropletprotein sensorself-assembled monolayer (SAM) |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Tzu-Chun Liao J. Andrew Yeh |
spellingShingle |
Tzu-Chun Liao J. Andrew Yeh Microdroplet Protein Sensors on a Gold Surface with a Self-assembled Monolayer Treatment International Journal of Automation and Smart Technology microdroplet protein sensor self-assembled monolayer (SAM) |
author_facet |
Tzu-Chun Liao J. Andrew Yeh |
author_sort |
Tzu-Chun Liao |
title |
Microdroplet Protein Sensors on a Gold Surface with a Self-assembled Monolayer Treatment |
title_short |
Microdroplet Protein Sensors on a Gold Surface with a Self-assembled Monolayer Treatment |
title_full |
Microdroplet Protein Sensors on a Gold Surface with a Self-assembled Monolayer Treatment |
title_fullStr |
Microdroplet Protein Sensors on a Gold Surface with a Self-assembled Monolayer Treatment |
title_full_unstemmed |
Microdroplet Protein Sensors on a Gold Surface with a Self-assembled Monolayer Treatment |
title_sort |
microdroplet protein sensors on a gold surface with a self-assembled monolayer treatment |
publisher |
Chinese Institute of Automation Engineers (CIAE) & Taiwan Smart Living Space Association (SMART LISA) |
series |
International Journal of Automation and Smart Technology |
issn |
2223-9766 |
publishDate |
2012-03-01 |
description |
<p>A new kind of microdroplet-based biological protein sensor is presented. The sensor was made by placing silicon oil on gold film with a self-assembled monolayer (SAM). The surface tension dominates the sensitivity of the sensor. Using mercaptoundecanoic acid (11-MUA) as the sensor’s SAM layer, the sensor can detect 0.5 mg/ml, 20 μg/ml, and 0.4 μg/ml bovine serum albumin (BSA) protein solutions in a control volume of 0.5ml. The sensor’s reaction time for concentrations of 0.5 mg/ml, 20 μg/ml, and 0.4μg/ml protein solutions was 15, 60 and 120 minutes, respectively. As the size of microdroplet decreased, the change of contact angle increased.</p> |
topic |
microdroplet protein sensor self-assembled monolayer (SAM) |
url |
http://www.ausmt.org/index.php/AUSMT/article/view/116 |
work_keys_str_mv |
AT tzuchunliao microdropletproteinsensorsonagoldsurfacewithaselfassembledmonolayertreatment AT jandrewyeh microdropletproteinsensorsonagoldsurfacewithaselfassembledmonolayertreatment |
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1725176804242620416 |