The Preparation of Fluorescence-Quenched Probes for Use in the Characterization of Human Factor Xa Substrate Binding Domains

The Preparation of Fluorescence-Quenched Probes for Use in the Characterization of Human Factor Xa Substrate Binding Domains

The preparation and characterization by LCMS of a library of 55 fluorescence- quenched peptides is described. The peptides bear a terminal anthranilamide fluorophore and a penultimate 2,4-dinitrophenyl-L-lysine quencher, and will be used to probe the substrate binding domain of the human blood coagu...

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Bibliographic Details
Main Authors: Peter J. Duggan, Julia Cianci, Karen M. Bromfield
Format: Article
Language:English
Published: MDPI AG 2004-05-01
Series:Molecules
Subjects:
Solid phase peptide synthesis
parallel synthesis
fluorescence-quenched substrates
protease
factor Xa.
Online Access:http://www.mdpi.com/1420-3049/9/6/427/

Internet

http://www.mdpi.com/1420-3049/9/6/427/

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