Silybin-Induced Apoptosis Occurs in Parallel to the Increase of Ceramides Synthesis and miRNAs Secretion in Human Hepatocarcinoma Cells
Silybin is a flavonolignan extracted from <i>Silybum marianum</i> (milk thistle) with hepatoprotective, antioxidant, and anti-inflammatory activity. Several studies have shown that silybin is highly effective to prevent and treat different types of cancer and that its antitumor mechanism...
Main Authors: | Silvia Zappavigna, Daniela Vanacore, Stefania Lama, Nicoletta Potenza, Aniello Russo, Pasquale Ferranti, Marcello Dallio, Alessandro Federico, Carmelina Loguercio, Pasquale Sperlongano, Michele Caraglia, Paola Stiuso |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-05-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/20/9/2190 |
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