Aggravation of chronic stress effects on hippocampal neurogenesis and spatial memory in LPA₁ receptor knockout mice.
The lysophosphatidic acid LPA₁ receptor regulates plasticity and neurogenesis in the adult hippocampus. Here, we studied whether absence of the LPA₁ receptor modulated the detrimental effects of chronic stress on hippocampal neurogenesis and spatial memory.Male LPA₁-null (NULL) and wild-type (WT) mi...
Main Authors: | Estela Castilla-Ortega, Carolina Hoyo-Becerra, Carmen Pedraza, Jerold Chun, Fernando Rodríguez De Fonseca, Guillermo Estivill-Torrús, Luis J Santín |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3183048?pdf=render |
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