Primary Angiitis of the Central Nervous System

Primary angiitis of the central nervous system (PACNS) is an idiopathic disorder (vasculitis) restricted to the central nervous system (CNS). It often presents with focal neurological deficits suggesting stroke or a combination of confusion and headache. We herein report three cases with various com...

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Main Authors: Hossein Pourmahmoodian, Hossein Ali Ghelichnia Omrani, Mohammad Hossein Harrirchian, Mojdeh Ghabaee, Babak Zamani, Majid Ghaffarpour
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2012-03-01
Series:Acta Medica Iranica
Subjects:
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/3886
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spelling doaj-d9b3b0ba5b9b4c319312eea8907b00442020-11-25T02:35:50ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942012-03-01503Primary Angiitis of the Central Nervous SystemHossein Pourmahmoodian0Hossein Ali Ghelichnia Omrani1Mohammad Hossein Harrirchian2Mojdeh Ghabaee3Babak Zamani4Majid Ghaffarpour5Department of Neurology, Iranian Center of Neurological Research, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.Department of Neurology, Iranian Center of Neurological Research, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.Department of Neurology, Iranian Center of Neurological Research, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.Department of Neurology, Iranian Center of Neurological Research, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.Department of Neurology, Iranian Center of Neurological Research, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.Department of Neurology, Iranian Center of Neurological Research, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.Primary angiitis of the central nervous system (PACNS) is an idiopathic disorder (vasculitis) restricted to the central nervous system (CNS). It often presents with focal neurological deficits suggesting stroke or a combination of confusion and headache. We herein report three cases with various combinations of fever, partial seizure, encephalopathy, paresis, headache and ataxia. One of them was initially treated as herpes simplex meningoencephalitis, but further investigations revealed primary angiitis. Primary angiitis of the CNS has protean manifestations and should always be considered in patients suspicious to have CNS infection or stroke, particularly who does not respond to the routine treatments. Clinical data, exclusion of differential diagnoses and typical angiography seem to be enough to justify the diagnosis in the majority of cases. https://acta.tums.ac.ir/index.php/acta/article/view/3886VasculitisCentral nervous systemAngiography
collection DOAJ
language English
format Article
sources DOAJ
author Hossein Pourmahmoodian
Hossein Ali Ghelichnia Omrani
Mohammad Hossein Harrirchian
Mojdeh Ghabaee
Babak Zamani
Majid Ghaffarpour
spellingShingle Hossein Pourmahmoodian
Hossein Ali Ghelichnia Omrani
Mohammad Hossein Harrirchian
Mojdeh Ghabaee
Babak Zamani
Majid Ghaffarpour
Primary Angiitis of the Central Nervous System
Acta Medica Iranica
Vasculitis
Central nervous system
Angiography
author_facet Hossein Pourmahmoodian
Hossein Ali Ghelichnia Omrani
Mohammad Hossein Harrirchian
Mojdeh Ghabaee
Babak Zamani
Majid Ghaffarpour
author_sort Hossein Pourmahmoodian
title Primary Angiitis of the Central Nervous System
title_short Primary Angiitis of the Central Nervous System
title_full Primary Angiitis of the Central Nervous System
title_fullStr Primary Angiitis of the Central Nervous System
title_full_unstemmed Primary Angiitis of the Central Nervous System
title_sort primary angiitis of the central nervous system
publisher Tehran University of Medical Sciences
series Acta Medica Iranica
issn 0044-6025
1735-9694
publishDate 2012-03-01
description Primary angiitis of the central nervous system (PACNS) is an idiopathic disorder (vasculitis) restricted to the central nervous system (CNS). It often presents with focal neurological deficits suggesting stroke or a combination of confusion and headache. We herein report three cases with various combinations of fever, partial seizure, encephalopathy, paresis, headache and ataxia. One of them was initially treated as herpes simplex meningoencephalitis, but further investigations revealed primary angiitis. Primary angiitis of the CNS has protean manifestations and should always be considered in patients suspicious to have CNS infection or stroke, particularly who does not respond to the routine treatments. Clinical data, exclusion of differential diagnoses and typical angiography seem to be enough to justify the diagnosis in the majority of cases.
topic Vasculitis
Central nervous system
Angiography
url https://acta.tums.ac.ir/index.php/acta/article/view/3886
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