Elucidating the Relationship Between Insomnia, Sex, and Cardiovascular Disease
Sex differences in cardiovascular disease (CVD) mortality have been attributed to differences in pathophysiology between men and women and to disparities in CVD management that disproportionately affect women compared to men. Similarly, there has been investigation of differences in the prevalence a...
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2020-12-01
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doaj-d9cc72a3f05e445bb8cfe494a391506b2020-12-23T00:03:21ZengSAGE PublishingGender and the Genome2470-29002020-12-01410.1177/2470289720980018Elucidating the Relationship Between Insomnia, Sex, and Cardiovascular DiseaseRebecca Leeds MD0Ari Shechter PhD1Carmela Alcantara PhD2Brooke Aggarwal EdD, MS3John Usseglio MPH4Marwah Abdalla MD, MPH5Nathalie Moise MD, MS6 Center for Family and Community Medicine, Columbia University Irving Medical Center, New York, NY, USA Center for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA Columbia University School of Social Work, New York, NY, USA Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA Augustus C. Long Health Sciences Library, Columbia University Irving Medical Center, New York, NY, USA Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA Center for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USASex differences in cardiovascular disease (CVD) mortality have been attributed to differences in pathophysiology between men and women and to disparities in CVD management that disproportionately affect women compared to men. Similarly, there has been investigation of differences in the prevalence and presentation of insomnia attributable to sex. Few studies have examined how sex and insomnia interact to influence CVD outcomes, however. In this review, we summarize the literature on sex-specific differences in the prevalence and presentation of insomnia as well as existing research regarding the relationship between insomnia and CVD outcomes as it pertains to sex. Research to date indicate that women are more likely to have insomnia than men, and there appear to be differential associations in the relation between insomnia and CVD by sex. We posit potential mechanisms of the relationship between sex, insomnia and CVD, discuss gaps in the existing literature, and provide commentary on future research needed in this area. Unraveling the complex relations between sex, insomnia, and CVD may help to explain sex-specific differences in CVD, and identify sex-specific strategies for promotion of cardiovascular health. Throughout this review, terms “men” and “women” are used as they are in the source literature, which does not differentiate between sex and gender. The implications of this are also discussed.https://doi.org/10.1177/2470289720980018 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Rebecca Leeds MD Ari Shechter PhD Carmela Alcantara PhD Brooke Aggarwal EdD, MS John Usseglio MPH Marwah Abdalla MD, MPH Nathalie Moise MD, MS |
spellingShingle |
Rebecca Leeds MD Ari Shechter PhD Carmela Alcantara PhD Brooke Aggarwal EdD, MS John Usseglio MPH Marwah Abdalla MD, MPH Nathalie Moise MD, MS Elucidating the Relationship Between Insomnia, Sex, and Cardiovascular Disease Gender and the Genome |
author_facet |
Rebecca Leeds MD Ari Shechter PhD Carmela Alcantara PhD Brooke Aggarwal EdD, MS John Usseglio MPH Marwah Abdalla MD, MPH Nathalie Moise MD, MS |
author_sort |
Rebecca Leeds MD |
title |
Elucidating the Relationship Between Insomnia, Sex, and Cardiovascular Disease |
title_short |
Elucidating the Relationship Between Insomnia, Sex, and Cardiovascular Disease |
title_full |
Elucidating the Relationship Between Insomnia, Sex, and Cardiovascular Disease |
title_fullStr |
Elucidating the Relationship Between Insomnia, Sex, and Cardiovascular Disease |
title_full_unstemmed |
Elucidating the Relationship Between Insomnia, Sex, and Cardiovascular Disease |
title_sort |
elucidating the relationship between insomnia, sex, and cardiovascular disease |
publisher |
SAGE Publishing |
series |
Gender and the Genome |
issn |
2470-2900 |
publishDate |
2020-12-01 |
description |
Sex differences in cardiovascular disease (CVD) mortality have been attributed to differences in pathophysiology between men and women and to disparities in CVD management that disproportionately affect women compared to men. Similarly, there has been investigation of differences in the prevalence and presentation of insomnia attributable to sex. Few studies have examined how sex and insomnia interact to influence CVD outcomes, however. In this review, we summarize the literature on sex-specific differences in the prevalence and presentation of insomnia as well as existing research regarding the relationship between insomnia and CVD outcomes as it pertains to sex. Research to date indicate that women are more likely to have insomnia than men, and there appear to be differential associations in the relation between insomnia and CVD by sex. We posit potential mechanisms of the relationship between sex, insomnia and CVD, discuss gaps in the existing literature, and provide commentary on future research needed in this area. Unraveling the complex relations between sex, insomnia, and CVD may help to explain sex-specific differences in CVD, and identify sex-specific strategies for promotion of cardiovascular health. Throughout this review, terms “men” and “women” are used as they are in the source literature, which does not differentiate between sex and gender. The implications of this are also discussed. |
url |
https://doi.org/10.1177/2470289720980018 |
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