Biphasic Calcium Phosphate Ceramics for Bone Regeneration and Tissue Engineering Applications
Biphasic calcium phosphates (BCP) have been sought after as biomaterials for the reconstruction of bone defects in maxillofacial, dental and orthopaedic applications. They have demonstrated proven biocompatibility, osteoconductivity, safety and predictability in in vitro, in vivo and clinical models...
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doaj-d9da01d079d7470a8e7f222eb983d4ac2020-11-24T22:31:48ZengMDPI AGMaterials1996-19442010-01-013281582610.3390/ma3020815Biphasic Calcium Phosphate Ceramics for Bone Regeneration and Tissue Engineering ApplicationsSonja Ellen LoboTreena Livingston ArinzehBiphasic calcium phosphates (BCP) have been sought after as biomaterials for the reconstruction of bone defects in maxillofacial, dental and orthopaedic applications. They have demonstrated proven biocompatibility, osteoconductivity, safety and predictability in in vitro, in vivo and clinical models. More recently, in vitro and in vivo studies have shown that BCP can be osteoinductive. In the field of tissue engineering, they represent promising scaffolds capable of carrying and modulating the behavior of stem cells. This review article will highlight the latest advancements in the use of BCP and the characteristics that create a unique microenvironment that favors bone regeneration. http://www.mdpi.com/1996-1944/3/2/815/calcium phosphate ceramicsbone reconstructiontissue engineeringstem cell |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sonja Ellen Lobo Treena Livingston Arinzeh |
spellingShingle |
Sonja Ellen Lobo Treena Livingston Arinzeh Biphasic Calcium Phosphate Ceramics for Bone Regeneration and Tissue Engineering Applications Materials calcium phosphate ceramics bone reconstruction tissue engineering stem cell |
author_facet |
Sonja Ellen Lobo Treena Livingston Arinzeh |
author_sort |
Sonja Ellen Lobo |
title |
Biphasic Calcium Phosphate Ceramics for Bone Regeneration and Tissue Engineering Applications |
title_short |
Biphasic Calcium Phosphate Ceramics for Bone Regeneration and Tissue Engineering Applications |
title_full |
Biphasic Calcium Phosphate Ceramics for Bone Regeneration and Tissue Engineering Applications |
title_fullStr |
Biphasic Calcium Phosphate Ceramics for Bone Regeneration and Tissue Engineering Applications |
title_full_unstemmed |
Biphasic Calcium Phosphate Ceramics for Bone Regeneration and Tissue Engineering Applications |
title_sort |
biphasic calcium phosphate ceramics for bone regeneration and tissue engineering applications |
publisher |
MDPI AG |
series |
Materials |
issn |
1996-1944 |
publishDate |
2010-01-01 |
description |
Biphasic calcium phosphates (BCP) have been sought after as biomaterials for the reconstruction of bone defects in maxillofacial, dental and orthopaedic applications. They have demonstrated proven biocompatibility, osteoconductivity, safety and predictability in in vitro, in vivo and clinical models. More recently, in vitro and in vivo studies have shown that BCP can be osteoinductive. In the field of tissue engineering, they represent promising scaffolds capable of carrying and modulating the behavior of stem cells. This review article will highlight the latest advancements in the use of BCP and the characteristics that create a unique microenvironment that favors bone regeneration. |
topic |
calcium phosphate ceramics bone reconstruction tissue engineering stem cell |
url |
http://www.mdpi.com/1996-1944/3/2/815/ |
work_keys_str_mv |
AT sonjaellenlobo biphasiccalciumphosphateceramicsforboneregenerationandtissueengineeringapplications AT treenalivingstonarinzeh biphasiccalciumphosphateceramicsforboneregenerationandtissueengineeringapplications |
_version_ |
1725736203495407616 |