HSF1 Attenuates LPS-Induced Acute Lung Injury in Mice by Suppressing Macrophage Infiltration

HSF1 Attenuates LPS-Induced Acute Lung Injury in Mice by Suppressing Macrophage Infiltration

Heat shock factor 1 (HSF1) is a transcription factor involved in the heat shock response and other biological processes. We have unveiled here an important role of HSF1 in acute lung injury (ALI). HSF1 knockout mice were used as a model of lipopolysaccharide- (LPS-) induced ALI. Lung damage was aggr...

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Bibliographic Details
Main Authors:	Tao Li, Gui Xiao, Sipin Tan, Xueyan Shi, Leijing Yin, Chuyi Tan, Jia Gu, Yanjuan Liu, Huafei Deng, Ke Liu, Meidong Liu, Huali Zhang, Xianzhong Xiao
Format:	Article
Language:	English
Published:	Hindawi Limited 2020-01-01
Series:	Oxidative Medicine and Cellular Longevity
Online Access:	http://dx.doi.org/10.1155/2020/1936580

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