The <i>LDLR</i>, <i>APOB</i>, and <i>PCSK9</i> Variants of Index Patients with Familial Hypercholesterolemia in Russia

The <i>LDLR</i>, <i>APOB</i>, and <i>PCSK9</i> Variants of Index Patients with Familial Hypercholesterolemia in Russia

Familial hypercholesterolemia (FH) is a common autosomal codominant disorder, characterized by elevated low-density lipoprotein cholesterol levels causing premature atherosclerotic cardiovascular disease. About 2900 variants of <i>LDLR</i>, <i>APOB</i>, and <i>PCSK9<...

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Bibliographic Details
Main Authors: Alexey Meshkov, Alexandra Ershova, Anna Kiseleva, Evgenia Zotova, Evgeniia Sotnikova, Anna Petukhova, Anastasia Zharikova, Pavel Malyshev, Tatyana Rozhkova, Anastasia Blokhina, Alena Limonova, Vasily Ramensky, Mikhail Divashuk, Zukhra Khasanova, Anna Bukaeva, Olga Kurilova, Olga Skirko, Maria Pokrovskaya, Valeriya Mikova, Ekaterina Snigir, Alexsandra Akinshina, Sergey Mitrofanov, Daria Kashtanova, Valentin Makarov, Valeriy Kukharchuk, Sergey Boytsov, Sergey Yudin, Oxana Drapkina
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Genes
Subjects:
familial hypercholesterolemia
Russian
whole genome sequencing
<i>LDLR</i>
<i>APOB</i>
<i>PCSK9</i>
Online Access:https://www.mdpi.com/2073-4425/12/1/66

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