Comparing local ancestry inference models in populations of two- and three-way admixture
Local ancestry estimation infers the regional ancestral origin of chromosomal segments in admixed populations using reference populations and a variety of statistical models. Integrating local ancestry into complex trait genetics has the potential to increase detection of genetic associations and im...
Main Authors: | Ryan Schubert, Angela Andaleon, Heather E. Wheeler |
---|---|
Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2020-10-01
|
Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/10090.pdf |
Similar Items
-
A method for inferring an individual’s genetic ancestry and degree of admixture associated with six major continental populations
by: Ondrej eLibiger, et al.
Published: (2013-01-01) -
Genetic ancestry, admixture and health determinants in Latin America
by: Emily T. Norris, et al.
Published: (2018-12-01) -
LAIT: a local ancestry inference toolkit
by: Daniel Hui, et al.
Published: (2017-09-01) -
Rapid adaptation to malaria facilitated by admixture in the human population of Cabo Verde
by: Iman Hamid, et al.
Published: (2021-01-01) -
Admixture with indigenous people helps local adaptation: admixture-enabled selection in Polynesians
by: Mariko Isshiki, et al.
Published: (2021-09-01)