Mapping Attenuation Determinants in Enterovirus-D68

Mapping Attenuation Determinants in Enterovirus-D68

Enterovirus (EV)-D68 has been associated with epidemics in the United Sates in 2014, 2016 and 2018. This study aims to identify potential viral virulence determinants. We found that neonatal type I interferon receptor knockout mice are susceptible to EV-D68 infection via intraperitoneal inoculation...

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Bibliographic Details
Main Authors: Ming Te Yeh, Sara Capponi, Adam Catching, Simone Bianco, Raul Andino
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Viruses
Subjects:
enterovirus
enterovirus-D68
virulence determinant
mouse model
infectious clones
VP3
Online Access:https://www.mdpi.com/1999-4915/12/8/867

Internet

https://www.mdpi.com/1999-4915/12/8/867

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