Urine-based antigen detection assay for diagnosis of visceral leishmaniasis using monoclonal antibodies specific for six protein biomarkers of Leishmania infantum / Leishmania donovani.

The development of an accurate protein-based antigen detection assay for diagnosis of active visceral leishmaniasis (VL) would represent a major clinical advance. VL is a serious and fatal disease caused by the parasites Leishmania infantum and Leishmania donovani. The gold standard confirmatory dia...

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Bibliographic Details
Main Authors: Claudia Abeijon, Fabiana Alves, Séverine Monnerat, Jane Mbui, Agostinho G Viana, Raquel M Almeida, Lilian L Bueno, Ricardo T Fujiwara, Antonio Campos-Neto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008246