Understanding Immune Thrombocytopenia: Looking Out of the Box

The pathogenesis of immune thrombocytopenia (ITP) is increasingly being elucidated, and its etiology is becoming more frequently identified, leading to a diagnostic shift from primary to secondary ITP. The overlap between autoimmunity, immunodeficiency, and cancer is evident, implying more interdisc...

Full description

Bibliographic Details
Main Authors:	Alexandra Schifferli, Franco Cavalli, Bertrand Godeau, Howard A. Liebman, Mike Recher, Paul Imbach, Thomas Kühne
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-06-01
Series:	Frontiers in Medicine
Subjects:	immune thrombocytopenia ITP syndrome secondary ITP autoimmunity immunodeficiency cancer
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2021.613192/full

id	doaj-da64c461a33f4284bc63867435d6cd67
record_format	Article
spelling	doaj-da64c461a33f4284bc63867435d6cd672021-06-24T05:41:27ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2021-06-01810.3389/fmed.2021.613192613192Understanding Immune Thrombocytopenia: Looking Out of the BoxAlexandra Schifferli0Alexandra Schifferli1Franco Cavalli2Bertrand Godeau3Howard A. Liebman4Mike Recher5Paul Imbach6Thomas Kühne7Thomas Kühne8Department of Hematology/Oncology, University Children's Hospital Basel, Basel, SwitzerlandIntercontinental Cooperative Immune thrombocytopenia (ITP) Study Group, Basel, SwitzerlandLymphoma Unit, Oncology Institute of Southern Switzerland, Bellinzona, SwitzerlandCentre de Référence des Cytopénies Auto-Immunes de l'Adulte, Service de Médecine Interne, CHU Henri Mondor, AP-HP, Université Paris-Est Créteil, Créteil, FranceJane Anne Nohl Division of Hematology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, United StatesMedical Outpatient Clinic and Immunodeficiency Laboratory, Department of Biomedicine, University Hospital and University Basel, Basel, SwitzerlandIntercontinental Cooperative Immune thrombocytopenia (ITP) Study Group, Basel, SwitzerlandDepartment of Hematology/Oncology, University Children's Hospital Basel, Basel, SwitzerlandIntercontinental Cooperative Immune thrombocytopenia (ITP) Study Group, Basel, SwitzerlandThe pathogenesis of immune thrombocytopenia (ITP) is increasingly being elucidated, and its etiology is becoming more frequently identified, leading to a diagnostic shift from primary to secondary ITP. The overlap between autoimmunity, immunodeficiency, and cancer is evident, implying more interdisciplinarity in daily care. This mini-review is based on an expert meeting on ITP organized by the Intercontinental Cooperative ITP Study Group and presents the challenges of hematologists in understanding and investigating “out of the box” concepts associated with ITP.https://www.frontiersin.org/articles/10.3389/fmed.2021.613192/fullimmune thrombocytopeniaITP syndromesecondary ITPautoimmunityimmunodeficiencycancer
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Alexandra Schifferli Alexandra Schifferli Franco Cavalli Bertrand Godeau Howard A. Liebman Mike Recher Paul Imbach Thomas Kühne Thomas Kühne
spellingShingle	Alexandra Schifferli Alexandra Schifferli Franco Cavalli Bertrand Godeau Howard A. Liebman Mike Recher Paul Imbach Thomas Kühne Thomas Kühne Understanding Immune Thrombocytopenia: Looking Out of the Box Frontiers in Medicine immune thrombocytopenia ITP syndrome secondary ITP autoimmunity immunodeficiency cancer
author_facet	Alexandra Schifferli Alexandra Schifferli Franco Cavalli Bertrand Godeau Howard A. Liebman Mike Recher Paul Imbach Thomas Kühne Thomas Kühne
author_sort	Alexandra Schifferli
title	Understanding Immune Thrombocytopenia: Looking Out of the Box
title_short	Understanding Immune Thrombocytopenia: Looking Out of the Box
title_full	Understanding Immune Thrombocytopenia: Looking Out of the Box
title_fullStr	Understanding Immune Thrombocytopenia: Looking Out of the Box
title_full_unstemmed	Understanding Immune Thrombocytopenia: Looking Out of the Box
title_sort	understanding immune thrombocytopenia: looking out of the box
publisher	Frontiers Media S.A.
series	Frontiers in Medicine
issn	2296-858X
publishDate	2021-06-01
description	The pathogenesis of immune thrombocytopenia (ITP) is increasingly being elucidated, and its etiology is becoming more frequently identified, leading to a diagnostic shift from primary to secondary ITP. The overlap between autoimmunity, immunodeficiency, and cancer is evident, implying more interdisciplinarity in daily care. This mini-review is based on an expert meeting on ITP organized by the Intercontinental Cooperative ITP Study Group and presents the challenges of hematologists in understanding and investigating “out of the box” concepts associated with ITP.
topic	immune thrombocytopenia ITP syndrome secondary ITP autoimmunity immunodeficiency cancer
url	https://www.frontiersin.org/articles/10.3389/fmed.2021.613192/full
work_keys_str_mv	AT alexandraschifferli understandingimmunethrombocytopenialookingoutofthebox AT alexandraschifferli understandingimmunethrombocytopenialookingoutofthebox AT francocavalli understandingimmunethrombocytopenialookingoutofthebox AT bertrandgodeau understandingimmunethrombocytopenialookingoutofthebox AT howardaliebman understandingimmunethrombocytopenialookingoutofthebox AT mikerecher understandingimmunethrombocytopenialookingoutofthebox AT paulimbach understandingimmunethrombocytopenialookingoutofthebox AT thomaskuhne understandingimmunethrombocytopenialookingoutofthebox AT thomaskuhne understandingimmunethrombocytopenialookingoutofthebox
_version_	1721361609823092736

Understanding Immune Thrombocytopenia: Looking Out of the Box

Similar Items