D11-Mediated Inhibition of Protein Kinase CK2 Impairs HIF-1α-Mediated Signaling in Human Glioblastoma Cells

D11-Mediated Inhibition of Protein Kinase CK2 Impairs HIF-1α-Mediated Signaling in Human Glioblastoma Cells

Compelling evidence indicates that protein kinase CK2 plays an important role in many steps of cancer initiation and progression, therefore, the development of effective and cell-permeable inhibitors targeting this kinase has become an important objective for the treatment of a variety of cancer typ...

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Bibliographic Details
Main Authors: Susanne Schaefer, Tina H. Svenstrup, Mette Fischer, Barbara Guerra
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Pharmaceuticals
Subjects:
CK2
D11
HIF-1α
glioblastoma cells
gene expression profiling
Online Access:http://www.mdpi.com/1424-8247/10/1/5

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