Adult-onset adrenoleukodystrophy presenting as a psychiatric disorder: MRI findings

Adult-onset adrenoleukodystrophy presenting as a psychiatric disorder: MRI findings

ABSTRACT A 35-year-old, previously healthy man presented psychiatric symptoms lasting four years, receiving treatment with neuroleptics. One year later he evolved with gait disequilibrium. After a further six months, cognitive symptoms were characterized with rapid evolution to a profound demented s...

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Bibliographic Details
Main Authors: Antonio Cézar Ribeiro Galvão, Gislaine Cristina Lopes Machado-Porto, Fábio Henrique de Gobbi Porto, Leandro Tavares Lucato, Ricardo Nitrini
Format: Article
Language:English
Published: Associação Neurologia Cognitiva e do Comportamento
Series:Dementia & Neuropsychologia
Subjects:
leukoencephalopathies
leukodystrophies
adult-onset adrenoleukodystrophy
magnetic resonance imaging
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642012000400290&lng=en&tlng=en
Description
Summary:ABSTRACT A 35-year-old, previously healthy man presented psychiatric symptoms lasting four years, receiving treatment with neuroleptics. One year later he evolved with gait disequilibrium. After a further six months, cognitive symptoms were characterized with rapid evolution to a profound demented state. MRI showed signal changes in cerebral white matter and very long-chain fatty acids were detected in blood.
ISSN:1980-5764

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