Assessment of iron status and interplay between lipid peroxidation and antioxidant capacity in common hemoglobin variants in Osun State, southwestern Nigeria

Assessment of iron status and interplay between lipid peroxidation and antioxidant capacity in common hemoglobin variants in Osun State, southwestern Nigeria

INTRODUCTION Hemoglobin (Hb) and iron are prooxidants in nature and sources of free radicals in the biological system of all Hb phenotypes. Recent evidence linked abnormal hemoglobin S and C (HbSC) in sickle cell disease (SCD) to various complications in multiple oxidative processes. However, simila...

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Bibliographic Details
Main Authors: Kabiru A. Ajibola, Kamoru A. Adedokun, Taofeeq Oduola, Dolapo P. Oparinde, Olubunmi G. Ayelagbe, Hammed O. Ojokuku
Format: Article
Language:English
Published: Wiley 2019-06-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
antioxidant status
hemoglobin variants
iron status
lipid peroxidation
sickle cell disease
Online Access:https://doi.org/10.1002/kjm2.12062

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