Proinflammatory and prothrombotic effects on human vascular endothelial cells of Immune-cell-derived LIGHT

<p>Abstract</p> <p>Objective</p> <p>LIGHT (TNFSF 14) belongs to the tumor necrosis factor superfamily and is expressed by activated T cells as well as various types of antigen presenting cells. LIGHT binds to its cellular receptors TR2 and LTßR and has a co-stimulatory...

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Bibliographic Details
Main Authors: Celik S, Shankar V, Richter A, Hippe H-J, Akhavanpoor M, Bea F, Erbel C, Urban S, Blank N, Wambsganss N, Katus HA, Dengler TJ
Format: Article
Language:English
Published: BMC 2009-04-01
Series:European Journal of Medical Research
Subjects:
Online Access:http://www.eurjmedres.com/content/14/4/147