Proinflammatory and prothrombotic effects on human vascular endothelial cells of Immune-cell-derived LIGHT
<p>Abstract</p> <p>Objective</p> <p>LIGHT (TNFSF 14) belongs to the tumor necrosis factor superfamily and is expressed by activated T cells as well as various types of antigen presenting cells. LIGHT binds to its cellular receptors TR2 and LTßR and has a co-stimulatory...
Main Authors: | Celik S, Shankar V, Richter A, Hippe H-J, Akhavanpoor M, Bea F, Erbel C, Urban S, Blank N, Wambsganss N, Katus HA, Dengler TJ |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-04-01
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Series: | European Journal of Medical Research |
Subjects: | |
Online Access: | http://www.eurjmedres.com/content/14/4/147 |
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