The adsorption of biological peptides and proteins at the oil/water interface. A potentially important but largely unexplored field

This review focuses on some new techniques to study the behavior of peptides and proteins bound to oil droplets. We will show how model peptides e.g., amphipathic α helices (AαH) and amphipathic β strand (AβS) and some apolipoproteins adsorb to triacylglycerol (TAG) droplets and how they behave once...

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Main Authors: Donald M. Small, Libo Wang, Matthew A. Mitsche
Format: Article
Language:English
Published: Elsevier 2009-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520306349
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spelling doaj-dadbbb59acca48cdb7ae71cc883ca2b82021-04-28T05:55:57ZengElsevierJournal of Lipid Research0022-22752009-01-0150S329S334The adsorption of biological peptides and proteins at the oil/water interface. A potentially important but largely unexplored fieldDonald M. Small0Libo Wang1Matthew A. Mitsche2To whom correspondence should be addressed; Department of Physiology and Biophysics, Boston University School of Medicine, 700 Albany Street, W-302, Boston, MA 02118Department of Physiology and Biophysics, Boston University School of Medicine, 700 Albany Street, W-302, Boston, MA 02118Department of Physiology and Biophysics, Boston University School of Medicine, 700 Albany Street, W-302, Boston, MA 02118This review focuses on some new techniques to study the behavior of peptides and proteins bound to oil droplets. We will show how model peptides e.g., amphipathic α helices (AαH) and amphipathic β strand (AβS) and some apolipoproteins adsorb to triacylglycerol (TAG) droplets and how they behave once adsorbed to the interface. While most of the studies described involve peptides and proteins at an oil/water interface, studies can also be carried out when the surface has been partially covered with phospholipids. This work is important because it examines biophysical changes that take place at lipid droplet interfaces and how this may relate to the metabolism of lipoproteins and lipid droplets.http://www.sciencedirect.com/science/article/pii/S0022227520306349lipid dropletsoil dropletsfat bodiesadiposomesobesityapolipoproteins
collection DOAJ
language English
format Article
sources DOAJ
author Donald M. Small
Libo Wang
Matthew A. Mitsche
spellingShingle Donald M. Small
Libo Wang
Matthew A. Mitsche
The adsorption of biological peptides and proteins at the oil/water interface. A potentially important but largely unexplored field
Journal of Lipid Research
lipid droplets
oil droplets
fat bodies
adiposomes
obesity
apolipoproteins
author_facet Donald M. Small
Libo Wang
Matthew A. Mitsche
author_sort Donald M. Small
title The adsorption of biological peptides and proteins at the oil/water interface. A potentially important but largely unexplored field
title_short The adsorption of biological peptides and proteins at the oil/water interface. A potentially important but largely unexplored field
title_full The adsorption of biological peptides and proteins at the oil/water interface. A potentially important but largely unexplored field
title_fullStr The adsorption of biological peptides and proteins at the oil/water interface. A potentially important but largely unexplored field
title_full_unstemmed The adsorption of biological peptides and proteins at the oil/water interface. A potentially important but largely unexplored field
title_sort adsorption of biological peptides and proteins at the oil/water interface. a potentially important but largely unexplored field
publisher Elsevier
series Journal of Lipid Research
issn 0022-2275
publishDate 2009-01-01
description This review focuses on some new techniques to study the behavior of peptides and proteins bound to oil droplets. We will show how model peptides e.g., amphipathic α helices (AαH) and amphipathic β strand (AβS) and some apolipoproteins adsorb to triacylglycerol (TAG) droplets and how they behave once adsorbed to the interface. While most of the studies described involve peptides and proteins at an oil/water interface, studies can also be carried out when the surface has been partially covered with phospholipids. This work is important because it examines biophysical changes that take place at lipid droplet interfaces and how this may relate to the metabolism of lipoproteins and lipid droplets.
topic lipid droplets
oil droplets
fat bodies
adiposomes
obesity
apolipoproteins
url http://www.sciencedirect.com/science/article/pii/S0022227520306349
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