Ultrasound promoted green synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles
A highly efficient, eco-friendly and one-pot synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles was developed involving the reaction of 2-acetyl benzofurans and 5-mercapto-3-(4-chlorophenyl)-1,2,4triazole in the presence of molecular iodine under ultrasonic conditions to give 5-(ben...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2017-02-01
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Series: | Green Processing and Synthesis |
Subjects: | |
Online Access: | https://doi.org/10.1515/gps-2016-0099 |
Summary: | A highly efficient, eco-friendly and one-pot synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles was developed involving the reaction of 2-acetyl benzofurans and 5-mercapto-3-(4-chlorophenyl)-1,2,4triazole in the presence of molecular iodine under ultrasonic conditions to give 5-(benzofuran-2-yl)-acylthio-3-(4-chlorophenyl)-1,2,4triazoles, which was further cyclised using Eaton’s reagent under microwave conditions to give 5-(benzofuran-2-yl)-2-(4-chlorophenyl)thiazolo[3,2-b][1,2,4]triazoles. |
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ISSN: | 2191-9542 2191-9550 |