Ultrasound promoted green synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles

A highly efficient, eco-friendly and one-pot synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles was developed involving the reaction of 2-acetyl benzofurans and 5-mercapto-3-(4-chlorophenyl)-1,2,4triazole in the presence of molecular iodine under ultrasonic conditions to give 5-(ben...

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Main Authors: Kumar Surender, Sharma Dinesh Kumar
Format: Article
Language:English
Published: De Gruyter 2017-02-01
Series:Green Processing and Synthesis
Subjects:
Online Access:https://doi.org/10.1515/gps-2016-0099
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spelling doaj-dae8d7994c324276be960e2b14b3fb572021-10-02T19:10:00ZengDe GruyterGreen Processing and Synthesis2191-95422191-95502017-02-0161737710.1515/gps-2016-0099Ultrasound promoted green synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazolesKumar Surender0Sharma Dinesh Kumar1Department of Chemistry, Technological Institute of Textile and Sciences, Bhiwani, 127021, IndiaDepartment of Chemistry, Kishanlal Public College, Rewari, 123401, IndiaA highly efficient, eco-friendly and one-pot synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles was developed involving the reaction of 2-acetyl benzofurans and 5-mercapto-3-(4-chlorophenyl)-1,2,4triazole in the presence of molecular iodine under ultrasonic conditions to give 5-(benzofuran-2-yl)-acylthio-3-(4-chlorophenyl)-1,2,4triazoles, which was further cyclised using Eaton’s reagent under microwave conditions to give 5-(benzofuran-2-yl)-2-(4-chlorophenyl)thiazolo[3,2-b][1,2,4]triazoles.https://doi.org/10.1515/gps-2016-00995-(benzofuran-2-yl)-2-(4-chlorophenyl)thiazolo[3,2-b][1,2,4]triazoles5-(benzofuran-2-yl)-acylthio-3-(4-chlorophenyl)-1,2,4triazoles5-mercapto-3-(4-chlorophenyl)-1,2,4triazolemicrowave conditionsultrasonic conditions
collection DOAJ
language English
format Article
sources DOAJ
author Kumar Surender
Sharma Dinesh Kumar
spellingShingle Kumar Surender
Sharma Dinesh Kumar
Ultrasound promoted green synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles
Green Processing and Synthesis
5-(benzofuran-2-yl)-2-(4-chlorophenyl)thiazolo[3,2-b][1,2,4]triazoles
5-(benzofuran-2-yl)-acylthio-3-(4-chlorophenyl)-1,2,4triazoles
5-mercapto-3-(4-chlorophenyl)-1,2,4triazole
microwave conditions
ultrasonic conditions
author_facet Kumar Surender
Sharma Dinesh Kumar
author_sort Kumar Surender
title Ultrasound promoted green synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles
title_short Ultrasound promoted green synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles
title_full Ultrasound promoted green synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles
title_fullStr Ultrasound promoted green synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles
title_full_unstemmed Ultrasound promoted green synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles
title_sort ultrasound promoted green synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles
publisher De Gruyter
series Green Processing and Synthesis
issn 2191-9542
2191-9550
publishDate 2017-02-01
description A highly efficient, eco-friendly and one-pot synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles was developed involving the reaction of 2-acetyl benzofurans and 5-mercapto-3-(4-chlorophenyl)-1,2,4triazole in the presence of molecular iodine under ultrasonic conditions to give 5-(benzofuran-2-yl)-acylthio-3-(4-chlorophenyl)-1,2,4triazoles, which was further cyclised using Eaton’s reagent under microwave conditions to give 5-(benzofuran-2-yl)-2-(4-chlorophenyl)thiazolo[3,2-b][1,2,4]triazoles.
topic 5-(benzofuran-2-yl)-2-(4-chlorophenyl)thiazolo[3,2-b][1,2,4]triazoles
5-(benzofuran-2-yl)-acylthio-3-(4-chlorophenyl)-1,2,4triazoles
5-mercapto-3-(4-chlorophenyl)-1,2,4triazole
microwave conditions
ultrasonic conditions
url https://doi.org/10.1515/gps-2016-0099
work_keys_str_mv AT kumarsurender ultrasoundpromotedgreensynthesisofbenzofuransubstitutedthiazolo32b124triazoles
AT sharmadineshkumar ultrasoundpromotedgreensynthesisofbenzofuransubstitutedthiazolo32b124triazoles
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