The Quantitative Assessment of Imaging Features for the Study of Hirayama Disease Progression
Objective. To evaluate the forward shifting of cervical spinal cords in different segments of patients with Hirayama disease to determine whether the disease is self-limiting. Methods. This study was performed on 11 healthy subjects and 64 patients. According to the duration, the patients were divid...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2015-01-01
|
Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2015/803148 |
id |
doaj-daf12dd7856c43b785bafb62d286f07c |
---|---|
record_format |
Article |
spelling |
doaj-daf12dd7856c43b785bafb62d286f07c2020-11-25T01:40:25ZengHindawi LimitedBioMed Research International2314-61332314-61412015-01-01201510.1155/2015/803148803148The Quantitative Assessment of Imaging Features for the Study of Hirayama Disease ProgressionMinghao Shao0Jun Yin1Feizhou Lu2Chaojun Zheng3Hongli Wang4Jianyuan Jiang5Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai 200040, ChinaDepartment of Orthopedics, Huashan Hospital, Fudan University, Shanghai 200040, ChinaDepartment of Orthopedics, Huashan Hospital, Fudan University, Shanghai 200040, ChinaDepartment of Orthopedics, Huashan Hospital, Fudan University, Shanghai 200040, ChinaDepartment of Orthopedics, Huashan Hospital, Fudan University, Shanghai 200040, ChinaDepartment of Orthopedics, Huashan Hospital, Fudan University, Shanghai 200040, ChinaObjective. To evaluate the forward shifting of cervical spinal cords in different segments of patients with Hirayama disease to determine whether the disease is self-limiting. Methods. This study was performed on 11 healthy subjects and 64 patients. According to the duration, the patients were divided into 5 groups (≤1 year, 1-2 years, 2-3 years, 3-4 years, and ≥4 years). Cervical magnetic resonance imaging (MRI) of flexion and conventional position was performed. The distances between the posterior edge of the spinal cord and the cervical spinal canal (X), the anterior and posterior wall of the cervical spinal canal (Y), and the anterior-posterior (A) and the transverse diameter (B) of spinal cord cross sections were measured at different cervical spinal segments (C4 to T1). Results. In cervical flexion position, a significant increase in X/Y of C4-5 segments was found in groups 2–5, the C5-6 and C6-7 segments in groups 1–5, and the C7-T1 segments in group 5 (P<0.05). The degree of the increased X/Y and cervical flexion X/Y of C5-6 segments were different among the 5 groups (P<0.05), which was likely due to rapid increases in X/Y during the course of Hirayama’s disease. Conclusion. The X/Y change progression indicates that Hirayama disease may not be self-limiting.http://dx.doi.org/10.1155/2015/803148 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Minghao Shao Jun Yin Feizhou Lu Chaojun Zheng Hongli Wang Jianyuan Jiang |
spellingShingle |
Minghao Shao Jun Yin Feizhou Lu Chaojun Zheng Hongli Wang Jianyuan Jiang The Quantitative Assessment of Imaging Features for the Study of Hirayama Disease Progression BioMed Research International |
author_facet |
Minghao Shao Jun Yin Feizhou Lu Chaojun Zheng Hongli Wang Jianyuan Jiang |
author_sort |
Minghao Shao |
title |
The Quantitative Assessment of Imaging Features for the Study of Hirayama Disease Progression |
title_short |
The Quantitative Assessment of Imaging Features for the Study of Hirayama Disease Progression |
title_full |
The Quantitative Assessment of Imaging Features for the Study of Hirayama Disease Progression |
title_fullStr |
The Quantitative Assessment of Imaging Features for the Study of Hirayama Disease Progression |
title_full_unstemmed |
The Quantitative Assessment of Imaging Features for the Study of Hirayama Disease Progression |
title_sort |
quantitative assessment of imaging features for the study of hirayama disease progression |
publisher |
Hindawi Limited |
series |
BioMed Research International |
issn |
2314-6133 2314-6141 |
publishDate |
2015-01-01 |
description |
Objective. To evaluate the forward shifting of cervical spinal cords in different segments of patients with Hirayama disease to determine whether the disease is self-limiting. Methods. This study was performed on 11 healthy subjects and 64 patients. According to the duration, the patients were divided into 5 groups (≤1 year, 1-2 years, 2-3 years, 3-4 years, and ≥4 years). Cervical magnetic resonance imaging (MRI) of flexion and conventional position was performed. The distances between the posterior edge of the spinal cord and the cervical spinal canal (X), the anterior and posterior wall of the cervical spinal canal (Y), and the anterior-posterior (A) and the transverse diameter (B) of spinal cord cross sections were measured at different cervical spinal segments (C4 to T1). Results. In cervical flexion position, a significant increase in X/Y of C4-5 segments was found in groups 2–5, the C5-6 and C6-7 segments in groups 1–5, and the C7-T1 segments in group 5 (P<0.05). The degree of the increased X/Y and cervical flexion X/Y of C5-6 segments were different among the 5 groups (P<0.05), which was likely due to rapid increases in X/Y during the course of Hirayama’s disease. Conclusion. The X/Y change progression indicates that Hirayama disease may not be self-limiting. |
url |
http://dx.doi.org/10.1155/2015/803148 |
work_keys_str_mv |
AT minghaoshao thequantitativeassessmentofimagingfeaturesforthestudyofhirayamadiseaseprogression AT junyin thequantitativeassessmentofimagingfeaturesforthestudyofhirayamadiseaseprogression AT feizhoulu thequantitativeassessmentofimagingfeaturesforthestudyofhirayamadiseaseprogression AT chaojunzheng thequantitativeassessmentofimagingfeaturesforthestudyofhirayamadiseaseprogression AT hongliwang thequantitativeassessmentofimagingfeaturesforthestudyofhirayamadiseaseprogression AT jianyuanjiang thequantitativeassessmentofimagingfeaturesforthestudyofhirayamadiseaseprogression AT minghaoshao quantitativeassessmentofimagingfeaturesforthestudyofhirayamadiseaseprogression AT junyin quantitativeassessmentofimagingfeaturesforthestudyofhirayamadiseaseprogression AT feizhoulu quantitativeassessmentofimagingfeaturesforthestudyofhirayamadiseaseprogression AT chaojunzheng quantitativeassessmentofimagingfeaturesforthestudyofhirayamadiseaseprogression AT hongliwang quantitativeassessmentofimagingfeaturesforthestudyofhirayamadiseaseprogression AT jianyuanjiang quantitativeassessmentofimagingfeaturesforthestudyofhirayamadiseaseprogression |
_version_ |
1725045991857455104 |