Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells

Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells

Background: Marrow adipose tissue (MAT) has been shown to be vital for regulating metabolism and maintaining skeletal homeostasis in the bone marrow (BM) niche. As a reflection of BM remodeling, MAT is highly responsive to nutrient fluctuations, hormonal changes, and metabolic disturbances such as o...

Full description

Bibliographic Details
Main Authors: Nicole Aaron, Michael J Kraakman, Qiuzhong Zhou, Qiongming Liu, Samantha Costa, Jing Yang, Longhua Liu, Lexiang Yu, Liheng Wang, Ying He, Lihong Fan, Hiroyuki Hirakawa, Lei Ding, James Lo, Weidong Wang, Baohong Zhao, Edward Guo, Lei Sun, Cliff J Rosen, Li Qiang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-06-01
Series:eLife
Subjects:
adipsin
bone marrow adiposity
complement
PPARgamma
adipokine
Online Access:https://elifesciences.org/articles/69209

Similar Items

Similar Items