Linking mPFC circuit maturation to the developmental regulation of emotional memory and cognitive flexibility

Linking mPFC circuit maturation to the developmental regulation of emotional memory and cognitive flexibility

The medial prefrontal cortex (mPFC) and its abundant connections with other brain regions play key roles in memory, cognition, decision making, social behaviors, and mood. Dysfunction in mPFC is implicated in psychiatric disorders in which these behaviors go awry. The prolonged maturation of mPFC li...

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Bibliographic Details
Main Authors: Cassandra B Klune, Benita Jin, Laura A DeNardo
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-05-01
Series:eLife
Subjects:
mPFC
development
circuit
synapse
cognitive flexibility
memory
Online Access:https://elifesciences.org/articles/64567

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