Modeling perinatal mortality in twins via generalized additive mixed models: a comparison of estimation approaches

Modeling perinatal mortality in twins via generalized additive mixed models: a comparison of estimation approaches

Abstract Background The analysis of twin data presents a unique challenge. Second-born twins on average weigh less than first-born twins and have an elevated risk of perinatal mortality. It is not clear whether the risk difference depends on birth order or their relative birth weight. This study eva...

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Bibliographic Details
Main Authors: Muhammad Abu Shadeque Mullah, James A. Hanley, Andrea Benedetti
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Medical Research Methodology
Subjects:
Penalized splines
Generalized linear mixed models
Penalized quasi-likelihood
Laplace approximation
Markov chain Monte Carlo
Variance components
Online Access:http://link.springer.com/article/10.1186/s12874-019-0861-2

Internet

http://link.springer.com/article/10.1186/s12874-019-0861-2

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