Two Distinct Mechanisms Govern RpoS-Mediated Repression of Tick-Phase Genes during Mammalian Host Adaptation by Borrelia burgdorferi, the Lyme Disease Spirochete
The alternative sigma factor RpoS plays a key role modulating gene expression in Borrelia burgdorferi, the Lyme disease spirochete, by transcribing mammalian host-phase genes and repressing σ70-dependent genes required within the arthropod vector. To identify cis regulatory elements involved in RpoS...
Main Authors: | Arianna P. Grove, Dionysios Liveris, Radha Iyer, Mary Petzke, Joseph Rudman, Melissa J. Caimano, Justin D. Radolf, Ira Schwartz, Patricia A. Rosa |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2017-08-01
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Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/8/4/e01204-17 |
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