Gene Polymorphisms Affect the Effectiveness of Atorvastatin in Treating Ischemic Stroke Patients

Gene Polymorphisms Affect the Effectiveness of Atorvastatin in Treating Ischemic Stroke Patients

Background/Aims: The aim of the present study is to investigate whether the single nucleotide polymorphism (SNP) in lipid metabolism related genes would affect the effectiveness of atorvastatin in both Han and Uighur populations. Methods: 200 ischemic stroke patients were treated with atorvastatin....

Full description

Bibliographic Details
Main Authors:	Yun-Hua Yue, Xu-dong Bai, Hui-jun Zhang, You-mei Li, Liang Hu, Ling-yun Liu, Jie-ping Mao, Xiao-ying Yang, Na-mu Dila
Format:	Article
Language:	English
Published:	Cell Physiol Biochem Press GmbH & Co KG 2016-07-01
Series:	Cellular Physiology and Biochemistry
Subjects:	Atorvastatin Ischemic stroke Lipid metabolism related gene SNP Single nucleotide polymorphism
Online Access:	http://www.karger.com/Article/FullText/445654

Similar Items

ANGPTL4 variants and their haplotypes are associated with serum lipid levels, the risk of coronary artery disease and ischemic stroke and atorvastatin cholesterol-lowering responses
by: Qian Yang, et al.
Published: (2018-10-01)

The association of lipid metabolism relative gene polymorphisms and ischemic stroke in Han and Uighur population of Xinjiang
by: Yun-hua Yue, et al.
Published: (2017-06-01)

ANTIATHEROGENIC AND PLEIOTROPIC ACTIVITY OF VARIOUS DOSES OF ATORVASTATIN IN PATIENTS WITH ISCHEMIC STROKE
by: M. G. Bubnova, et al.
Published: (2013-08-01)

Apolipoprotein E mRNA expression in mononuclear cells from normolipidemic and hypercholesterolemic individuals treated with atorvastatin
by: Cerda Alvaro, et al.
Published: (2011-11-01)

Single-Nucleotide Polymorphisms in Oxidative Stress-Related Genes and the Risk of a Stroke in a Polish Population—A Preliminary Study
by: Ewelina Synowiec, et al.
Published: (2021-03-01)

Association between single nucleotide polymorphism rs9534275 and the risk of coronary artery disease and ischemic stroke
by: Liu Miao, et al.
Published: (2017-10-01)

The 3’-UTR Polymorphisms in the Thymidylate Synthase (TS) Gene Associated with The Risk of Ischemic Stroke and Silent Brain Infarction
by: Jung Oh Kim, et al.
Published: (2021-03-01)

Association of the MMP-9 polymorphism and ischemic stroke risk in southern Chinese Han population
by: Ning Gao, et al.
Published: (2019-04-01)

A Workflow for Selection of Single Nucleotide Polymorphic Markers for Studying of Genetics of Ischemic Stroke Outcomes
by: Gennady Khvorykh, et al.
Published: (2021-02-01)

Role of cigarette smoking in the development of ischemic stroke and its subtypes: a Mendelian randomization study
by: Qian Y, et al.
Published: (2019-08-01)

Association between Single Nucleotide Polymorphism rs1044925 and the Risk of Coronary Artery Disease and Ischemic Stroke
by: Dong-Feng Wu, et al.
Published: (2014-02-01)

Study of associations of polymorphic variants of lipid metabolism genes and angiogenesis with first ischemic stroke
by: Veronika N. Shishkova, et al.
Published: (2019-02-01)

Pharmacogenetics of OATP Transporters Reveals That SLCO1B1 c.388A>G Variant Is Determinant of Increased Atorvastatin Response
by: Rosario D. C. Hirata, et al.
Published: (2011-09-01)

Interaction between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and environment with susceptibility to ischemic stroke in Chinese population
by: Xing-Zhen Zheng, et al.
Published: (2020-01-01)

Association of <i>NOTCH3</i> Gene Polymorphisms with Ischemic Stroke and Its Subtypes: A Meta-Analysis
by: Loo Keat Wei, et al.
Published: (2019-07-01)

Comparison of lipid profiles and inflammation in pre- and post-menopausal women with cerebral infarction and the role of atorvastatin in such populations
by: Jinhong Zhang, et al.
Published: (2018-02-01)

Effect of atorvastatin calcium on the carotid atherosclerotic plaque and cerebral blood flow indicators in patients with TIA
by: Jing Gao, et al.
Published: (2017-01-01)

ASSESSMENT OF THE POLYMORPHIC GENES VARIANTS OF THE LIPID AND CARBOHYDRATE METABOLISM, VASCULAR INFLAMMATION AND NEUROTRANSMITTER SYSTEM IN THE FIRST ISCHEMIC STROKE
by: V. N. Shishkova, et al.
Published: (2017-10-01)

Assessment of the Effect of HMGCR Variant Alleles on Response to Atorvastatin Treatment in Type 2 Diabetic Egyptian Patients
by: Sara Bakr Abd El-Kader1, et al.
Published: (2019-02-01)

Single nucleotide polymorphisms in the ANGPTL4 gene and the SNP-SNP interactions on the risk of atherosclerotic Ischaemic stroke
by: Chaoxiong Shen, et al.
Published: (2021-03-01)

Paraoxonase (PON1 and PON3) polymorphisms: impact on liver expression and atorvastatin-lactone hydrolysis
by: Stephan eRiedmaier, et al.
Published: (2011-07-01)

Association between the XKR6 rs7819412 SNP and serum lipid levels and the risk of coronary artery disease and ischemic stroke
by: Peng-Fei Zheng, et al.
Published: (2019-08-01)

The Effect of Atorvastatin on the Common Carotid Artery Intima-Media Thickness in Patients with Ischemic Stroke
by: Mojtaba Khazaei, et al.
Published: (2020-01-01)

The Role of Matrix Metalloproteinase Polymorphisms in Ischemic Stroke
by: Jason J. Chang, et al.
Published: (2016-08-01)

Association Between Circulating Linoleic Acid and Risk of Ischemic Stroke
by: Ding Ye, et al.
Published: (2021-01-01)

ANALYSIS OF COMPLEX CARRIER STATE OF GENETIC POLYMORPHISMS ASSOCIATED WITH VARIOUS ISCHEMIC STROKE TYPES
by: N. N. Strambovskaya
Published: (2015-09-01)

Tagging SNPs in the MTHFR Gene and Risk of Ischemic Stroke in a Chinese Population
by: Bao-Sheng Zhou, et al.
Published: (2014-05-01)

The effectiveness of atorvastatin in the prevention of stroke
by: O. D. Ostroumova, et al.
Published: (2015-12-01)

EFFICACY AND SAFETY OF THERAPY WITH ATORVASTATIN IN HIGH DOSES
by: A. N. Meshkov
Published: (2016-01-01)

APOE Polymorphisms Contribute to Reduced Atorvastatin Response in Chilean Amerindian Subjects
by: Jenny Lagos, et al.
Published: (2015-04-01)

Effect of ncRNA ANRIL on atherothrombotic stroke risk
by: Xiao-Ling Chen, et al.
Published: (2019-08-01)

Involvement of polymorphisms of the nerve growth factor and its receptor encoding genes in the etiopathogenesis of ischemic stroke
by: Ani Stepanyan, et al.
Published: (2018-03-01)

THE USE OF ATORVASTATIN FOR THE PREVENTION OF RECURRENT ATRIAL FIBRILLATION AFTER ELECTRICAL CARDIOVERSION IN PATIENTS WITH ISCHEMIC HEART DISEASE
by: S. N. Tereshchenko, et al.
Published: (2016-01-01)

DOCK7-ANGPTL3 SNPs and their haplotypes with serum lipid levels and the risk of coronary artery disease and ischemic stroke
by: Wei-Jun Li, et al.
Published: (2018-02-01)

Polymorphism in Integrin ITGA2 is Associated with Ischemic Stroke and Altered Serum Cholesterol in Chinese Individuals
by: Jian-Xia Lu, et al.
Published: (2014-03-01)

Lipid Profile in Patients with Ischemic and Hemorrhagic Stroke
by: Mohammad Saadatnia, et al.
Published: (2011-04-01)

The Connotation of Variances in the Risk Predictors, Medications, Homocysteine, and Homocysteine Pathway Gene Polymorphisms with CVA/Stroke
by: Rizwan Masud, et al.
Published: (2020-12-01)

Correlation between interleukin-18 promoter -607C/A polymorphism and susceptibility to ischemic stroke
by: Jian-xia Lu, et al.
Published: (2013-06-01)

Correlation between interleukin-18 promoter -607C/A polymorphism and susceptibility to ischemic stroke
by: Jian-xia Lu, et al.
Published: (2013-01-01)

STATINS IN PREVENTION OF ISCHEMIC STROKE
by: A. V. Susekov, et al.
Published: (2015-09-01)