Combining transposon mutagenesis and reporter genes to identify novel regulators of the topA promoter in Streptomyces

Abstract Background Identifying the regulatory factors that control transcriptional activity is a major challenge of gene expression studies. Here, we describe the application of a novel approach for in vivo identification of regulatory proteins that may directly or indirectly control the transcript...

Full description

Bibliographic Details
Main Authors: Martyna Gongerowska-Jac, Marcin Jan Szafran, Dagmara Jakimowicz
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Microbial Cell Factories
Subjects:
Online Access:https://doi.org/10.1186/s12934-021-01590-7

Similar Items