Automatic Coregistration Between Coronary Angiography and Intravascular Optical Coherence Tomography

• Main Authors: Hui Qin, MSc, Chunming Li, BSc, Yingguang Li, PhD, Jiayue Huang, MSc, Fan Yang, BSc, Takashi Kubo, MD, PhD, Takashi Akasaka, MD, PhD, Changyan Xiao, PhD, Juan Luis Gutiérrez-Chico, MD, PhD, Shengxian Tu, PhD
• Format: Article
• Language: English
• Published: Elsevier 2021-09-01
• Series: JACC: Asia
• Subjects: angiography; image registration; optical coherence tomography; percutaneous coronary intervention
• Online Access: http://www.sciencedirect.com/science/article/pii/S2772374721000715

This study sought to evaluate a novel approach for automatic coregistration of optical coherence tomography (OCT) and coronary angiography. Lumen diameters and side branches from both coronary angiography and OCT were used to create 2 feature sets. Subsequently, a 2-step coregistration approach was performed on the feature sets for matching of each OCT cross section on the angiographic centerline. For validation, all side branches with ≥1.0 mm diameter were identified and used as paired fiduciary landmarks. Geographical error was defined as the distance between the automatically coregistered and the true-paired landmarks. Altogether 212 vessels from 181 patients were analyzed. Mismatch of coronary angiography and OCT occurred in 64 of 1,530 reference landmarks. Median geographical error was 0.32 (interquartile range: 0.00-0.56) mm. The mean time for coregistration was 20.69 ± 1.07 seconds. In conclusion, fast and automatic coregistration of OCT and angiography using a single standard angiographic loop is feasible and accurate.