Design, Synthesis, and Antimicrobial Evaluation of New Annelated Pyrimido[2,1-<i>c</i>][1,2,4]triazolo[3,4-<i>f</i>][1,2,4]triazines

Design, Synthesis, and Antimicrobial Evaluation of New Annelated Pyrimido[2,1-<i>c</i>][1,2,4]triazolo[3,4-<i>f</i>][1,2,4]triazines

A series of 34 new pyrimido[2,1-<i>c</i>][1,2,4]triazine-3,4-diones were synthesized and fully characterized using IR, NMR, MS, and microanalytical analysis. In vitro investigation of 12 compounds of this series revealed promising antimicrobial activity of the conjugates <b>15a<...

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Bibliographic Details
Main Authors:	Islam H. El Azab, Nadia A.A. Elkanzi
Format:	Article
Language:	English
Published:	MDPI AG 2020-03-01
Series:	Molecules
Subjects:	mannich reaction 1,2,4-triazine pyrimidine 1,2,4-triazole <i>n</i>-heterocycles antimicrobial activity
Online Access:	https://www.mdpi.com/1420-3049/25/6/1339

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