Antifouling poly(N-(2-hydroxyethyl)acrylamide)/sodium alginate double network hydrogels with eminent mechanical properties

Antifouling poly(N-(2-hydroxyethyl)acrylamide)/sodium alginate double network hydrogels with eminent mechanical properties

In recent years, hydrogels with antifouling properties and good biocompatibility have attracted great attention in bio-devices, but most of them are lack of eminent mechanical properties that limit their practical application greatly. In this work, a newly hybrid ion-covalent cross-linked double net...

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Main Authors: Jing Zhang, Pai Peng, Lingdong Chen, Liping Zhao, Jie Feng
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Polymer Testing
Subjects:
Double network hydrogels
High mechanical properties
Antifouling
Online Access:http://www.sciencedirect.com/science/article/pii/S0142941821000374
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spelling doaj-db8a5fa48b144b419155ab0e99a0f83c2021-03-22T12:34:45ZengElsevierPolymer Testing0142-94182021-03-0195107087Antifouling poly(N-(2-hydroxyethyl)acrylamide)/sodium alginate double network hydrogels with eminent mechanical propertiesJing Zhang0Pai Peng1Lingdong Chen2Liping Zhao3Jie Feng4College of Materials Science & Engineering, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, ChinaCollege of Materials Science & Engineering, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, ChinaCollege of Materials Science & Engineering, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, ChinaThe Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, 314000, PR China; Corresponding authors. College of Materials Science & Engineering, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, China.College of Materials Science & Engineering, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, China; Corresponding authors. College of Materials Science & Engineering, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, China.In recent years, hydrogels with antifouling properties and good biocompatibility have attracted great attention in bio-devices, but most of them are lack of eminent mechanical properties that limit their practical application greatly. In this work, a newly hybrid ion-covalent cross-linked double network (DN) hydrogels with excellent antifouling as well as mechanical properties were prepared by a simple one-pot method based on sodium alginate and a kind of antifouling material, N-hydroxyethyl acrylamide (HEAA). The DN hydrogel have excellent mechanical properties, including high tensile strength (1.32 MPa), high elastic modulus (0.31 MPa) and preeminent fatigue resistance. Besides, the DN hydrogel have good antifouling properties suggested by protein adsorption and cell adhesion experiments. In addition, they also exhibit highly in vitro compatibility. These properties make the DN hydrogels suitable for application in different fields, such as tissue scaffolds, implantable devices and so on.http://www.sciencedirect.com/science/article/pii/S0142941821000374Double network hydrogelsHigh mechanical propertiesAntifouling
collection DOAJ
language English
format Article
sources DOAJ
author Jing Zhang
Pai Peng
Lingdong Chen
Liping Zhao
Jie Feng
spellingShingle Jing Zhang
Pai Peng
Lingdong Chen
Liping Zhao
Jie Feng
Antifouling poly(N-(2-hydroxyethyl)acrylamide)/sodium alginate double network hydrogels with eminent mechanical properties
Polymer Testing
Double network hydrogels
High mechanical properties
Antifouling
author_facet Jing Zhang
Pai Peng
Lingdong Chen
Liping Zhao
Jie Feng
author_sort Jing Zhang
title Antifouling poly(N-(2-hydroxyethyl)acrylamide)/sodium alginate double network hydrogels with eminent mechanical properties
title_short Antifouling poly(N-(2-hydroxyethyl)acrylamide)/sodium alginate double network hydrogels with eminent mechanical properties
title_full Antifouling poly(N-(2-hydroxyethyl)acrylamide)/sodium alginate double network hydrogels with eminent mechanical properties
title_fullStr Antifouling poly(N-(2-hydroxyethyl)acrylamide)/sodium alginate double network hydrogels with eminent mechanical properties
title_full_unstemmed Antifouling poly(N-(2-hydroxyethyl)acrylamide)/sodium alginate double network hydrogels with eminent mechanical properties
title_sort antifouling poly(n-(2-hydroxyethyl)acrylamide)/sodium alginate double network hydrogels with eminent mechanical properties
publisher Elsevier
series Polymer Testing
issn 0142-9418
publishDate 2021-03-01
description In recent years, hydrogels with antifouling properties and good biocompatibility have attracted great attention in bio-devices, but most of them are lack of eminent mechanical properties that limit their practical application greatly. In this work, a newly hybrid ion-covalent cross-linked double network (DN) hydrogels with excellent antifouling as well as mechanical properties were prepared by a simple one-pot method based on sodium alginate and a kind of antifouling material, N-hydroxyethyl acrylamide (HEAA). The DN hydrogel have excellent mechanical properties, including high tensile strength (1.32 MPa), high elastic modulus (0.31 MPa) and preeminent fatigue resistance. Besides, the DN hydrogel have good antifouling properties suggested by protein adsorption and cell adhesion experiments. In addition, they also exhibit highly in vitro compatibility. These properties make the DN hydrogels suitable for application in different fields, such as tissue scaffolds, implantable devices and so on.
topic Double network hydrogels
High mechanical properties
Antifouling
url http://www.sciencedirect.com/science/article/pii/S0142941821000374
work_keys_str_mv AT jingzhang antifoulingpolyn2hydroxyethylacrylamidesodiumalginatedoublenetworkhydrogelswitheminentmechanicalproperties
AT paipeng antifoulingpolyn2hydroxyethylacrylamidesodiumalginatedoublenetworkhydrogelswitheminentmechanicalproperties
AT lingdongchen antifoulingpolyn2hydroxyethylacrylamidesodiumalginatedoublenetworkhydrogelswitheminentmechanicalproperties
AT lipingzhao antifoulingpolyn2hydroxyethylacrylamidesodiumalginatedoublenetworkhydrogelswitheminentmechanicalproperties
AT jiefeng antifoulingpolyn2hydroxyethylacrylamidesodiumalginatedoublenetworkhydrogelswitheminentmechanicalproperties
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